Minoxidil Is a Potential Neuroprotective Drug for Paclitaxel-Induced Peripheral Neuropathy

    March 2017 in “ Scientific Reports ”
    Yifan Chen, Long Qing Chen, Yu Min Yeh … Meng Shen
    Studysummary This study found that minoxidil may protect against chemotherapy-induced peripheral neuropathy and potentially support hair recovery and tumor suppression in mouse models.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 10

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    2. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    3. Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes Skin Pharmacology and Physiology · 2009
    4. Minoxidil Opens Mitochondrial KATP Channels and Confers Cardioprotection British Journal of Pharmacology · 2004
    5. Chemotherapy-Induced Alopecia Southern Medical Journal · 1993
    6. Minoxidil: Inhibition of Proliferation of Keratinocytes In Vitro Journal of Investigative Dermatology · 1991
    7. The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers The Journal of Clinical Pharmacology · 1989
    8. Action of Topical Minoxidil in the Bald Stump-Tailed Macaque Journal of The American Academy of Dermatology · 1987
    9. Hypertrichosis Due to Minoxidil British Journal of Dermatology · 1979
    10. Hypertrichosis Due to Minoxidil British Journal of Dermatology · 1979

    Related research 1

    1. Minoxidil Is a Potential Neuroprotective Drug for Paclitaxel-Induced Peripheral Neuropathy Scientific Reports · 2017