Photothermal Conditioning of Platelet-Rich Plasma: Mechanisms and Emerging Applications in Hair Regeneration

The study investigates photothermal conditioning of platelet-rich plasma (PRP) as a novel method for hair regeneration, highlighting its potential to enhance PRP's bioactivity by increasing growth factor release and exosome production. This technique, which involves applying light and heat to PRP, may improve hair density, follicular regeneration, and prolong the anagen phase, with minimal adverse effects. However, the research is limited by small sample sizes, lack of standardized protocols, and short follow-up periods. Larger, randomized controlled trials are needed to confirm its efficacy and safety, but the method's autologous nature and regulatory approvals suggest promising clinical applications for treating hair loss.