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The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Testosterone may slow down wound healing and increase inflammation.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.

Certain gene variations are linked to higher male hormone levels in Chinese women with PCOS and insulin resistance.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Blocking β-catenin in skin cells improves hair growth during wound healing.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Androgens may block hair growth signals, targeting this could treat hair loss.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

NF-κB is crucial for different stages and types of hair growth in mice.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.

Understanding hair biology is key to developing better treatments for hair and scalp issues.