September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
144 citations,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
26 citations,
May 2015 in “Lasers in Surgery and Medicine” Laser treatment helped regrow hair in mice by activating a key growth pathway.
32 citations,
May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
277 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
January 2015 in “Springer eBooks” Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
54 citations,
November 2017 in “Scientific Reports” The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
24 citations,
March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
6 citations,
July 2007 in “Developmental Dynamics” The molecule Wise is involved in the development of various structures in chick embryos.
4 citations,
August 2020 in “Applied Materials Today” Hydrogel microcapsules help create cells that boost hair growth.
3 citations,
January 2023 in “Nutrients” Hordenine may help hair grow by activating a specific cell growth pathway.
3 citations,
January 2018 in “Biomedical dermatology” Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.
2 citations,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
124 citations,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
19 citations,
June 2020 in “Animals” Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.
15 citations,
August 2022 in “Journal of endocrinological investigation” Vitamin D and calcium are important for quick and effective skin wound healing.
1 citations,
November 2022 in “Frontiers in medicine” The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.
3 citations,
February 2022 in “Frontiers in Genetics” The LncRNA AC010789.1 slows down hair loss by promoting hair follicle growth and interacting with miR-21 and the Wnt/β-catenin pathway.
73 citations,
September 2016 in “Journal of Translational Medicine” Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
17 citations,
June 2020 in “Animals” lncRNAs may regulate hair follicle development in Hu sheep.
80 citations,
April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
May 2022 in “Gastroenterology” Targeting NETs may help reduce fibrosis in Crohn's disease.
1 citations,
April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
24 citations,
April 2020 in “Cells” DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.
October 2023 in “International journal of molecular sciences” Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Different types of human skin cells respond uniquely to various colors and doses of light, which could lead to specialized light treatments for skin conditions.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
September 2023 in “Frontiers in Medicine” The scalp fat tissue of men with hair loss shows changes in gene activity that may contribute to their condition.