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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The removal of the adrenal tumor improved the patient's symptoms and reduced androgen levels, indicating successful surgery.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Post-finasteride syndrome can cause lasting sexual, physical, and mental health issues with limited treatment options.

Certain Egyptian Sabal fruit extracts may help treat anti-androgenic diseases like benign prostatic hyperplasia.

Testosterone raises blood pressure and changes kidney protein levels.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.