research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
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research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Solid Effervescent Formulations as a New Approach for Topical Minoxidil Delivery
Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
research Iontophoresis-Targeted, Follicular Delivery of Minoxidil Sulfate for the Treatment of Alopecia
Iontophoresis improves minoxidil delivery for alopecia treatment.
research Iontophoresis of Minoxidil Sulphate Loaded Microparticles: A Strategy for Follicular Drug Targeting?
Iontophoresis improves minoxidil delivery to hair follicles for hair loss treatment.
research Investigation of the Cutaneous Penetration Behavior of Dexamethasone Loaded to Nano-Sized Lipid Particles by EPR Spectroscopy, and Confocal Raman and Laser Scanning Microscopy
Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.
research Germacrone and Sesquiterpene-Enriched Extracts from Curcuma Aeruginosa Roxb. Increase Skin Penetration of Minoxidil, a Hair Growth Promoter
Certain extracts from Curcuma aeruginosa Roxb. and germacrone can boost the skin's absorption of minoxidil, a hair growth promoter, making it more effective.
research An Open-Label Pilot Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.
research Morphological Characteristics and Notes of the Skin in Preclinical Toxicity Assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research Topical SCD-153, A 4-Methyl Itaconate Prodrug, For The Treatment Of Alopecia Areata
SCD-153 shows promise as an effective topical treatment for alopecia areata.
research Suspected Calcinosis Cutis and Demodicosis Secondary to Exogenous Steroid Administration in a Dog with Hypoadrenocorticism
A dog developed skin issues from too many steroids, but reducing steroids and using a specific treatment fixed the problems.
research Efficacy and Safety Evaluations of Topical Proretinal Nanoparticles
Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.
research Focal Alopecia in Dogs
Focal alopecia in dogs has many causes and requires various tests for accurate diagnosis and treatment.
research Diagnostic Approach to the Pruritic Cat
Finding the cause of a cat's itchiness requires a careful process and good communication with the owner.
research Data from Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The treatment was ineffective in humans.
research Novel Insights Into Ascorbic Acid Skin Permeation
The best way to apply vitamin C to the skin is with a nanostructured lipid carrier formulation.
research The Role of Oxidative Damage in Poor Scalp Health: Ramifications to Causality and Associated Hair Growth
Treating scalp issues with anti-dandruff shampoo improves hair health.
research Follicular Delivery of Caffeine from a Shampoo for Hair Retention
The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.
research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
research Targeted Delivery of Zinc Pyrithione to Skin Epithelia
Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.
research Rice Derivatives in Hair Protection
Rice derivatives in conditioners protect and improve hair health.
research Follicle-Targeted Delivery of Betamethasone and Minoxidil Co-Entrapped in Polymeric and Lipid Nanoparticles for Topical Alopecia Areata Treatment
Tiny particles improved delivery of hair loss treatments to hair follicles, with lipid-based particles performing best.
research Contemporary Techniques of Hair Replacement
In 1981, the punch graft technique was the main method for hair transplantation, and medical treatments for baldness were not very effective.
research Dermatophytosis in Cats: Clinical Signs and Identification of Etiological Agent
Most cats with dermatophytosis had fungal infections, mainly caused by M. canis.
research Sebum Production: Analysis, Impact, and Measurement Methods
Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.
research Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability
Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
research Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin
Hair follicles help attract immune cells to the skin during stress.
research Miz1 Is Required for Hair Follicle Structure and Hair Morphogenesis
Miz1 is essential for proper hair structure and growth.
research An Effective and Novel Technique for Hair Control in Craniofacial Surgery
A new method using bands and finger sheaths from gloves to manage hair during surgery is effective, quick, and reduces hair damage.
research Punch Hair Grafting Methods
The document recommends careful planning and techniques for successful punch hair grafting in hair restoration.