Topical SCD-153, A 4-Methyl Itaconate Prodrug, For The Treatment Of Alopecia Areata

    December 2022 in “ PNAS nexus ”
    Jerry Tsai, Sadakatali S. Gori, Jesse Alt … Luis A. Garza
    Studysummary In laboratory experiments, this study found that the topical prodrug SCD-153, a derivative of 4-methyl itaconate, reduced inflammation-related gene expression and induced significant hair growth in mice, suggesting it as a promising treatment candidate for alopecia areata.
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    Research cited in this study 21

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    9. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017
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    12. Health-Related Quality of Life Among Patients With Alopecia Areata: A Systematic Review Journal of The American Academy of Dermatology · 2016
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    17. British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012 British Journal of Dermatology · 2012
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