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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

A new vaccine using a porous scaffold boosts immunity and protects against the flu better than traditional methods.

New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.

Heat treatment increases hair loss in certain mice.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

People with alopecia areata have higher levels of osteopontin, which might be important in the disease's development, but this doesn't relate to how severe the disease is.

Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.

Punctate follicular porokeratosis is a skin condition with specific features seen in hair follicles.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

Certain bacteria can enhance skin regeneration.

People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Some drugs can cause skin reactions, which may improve when the drug is stopped, and rapid diagnosis and stopping the drug is crucial.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Taking vitamin D might improve life for MS patients and reduce skin side effects from alemtuzumab treatment.

Benign skin tumors need accurate diagnosis to ensure proper treatment.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.