Bacteria Induce Skin Regeneration

    G. Wang, H. Liu, Eric M. Wier, Roger V. Ortines, Nasif Islam, A. Li, Yunxia Xue, Y. Wang, Nathan Archer, Lloyd S. Miller, Luis A. Garza
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    TLDR Certain bacteria can enhance skin regeneration.
    The document from July 1, 2020, discusses various studies on tissue regeneration and wound healing. One study showed that porcine type I collagen peptides enhanced wound closure in both young and aged fibroblasts. Another study found that mice lacking the RNase L gene had improved regenerative capacity and faster wound healing due to IL-36 signaling. Trehalose was found to speed up the growth of epidermal sheets in a collagen gel, suggesting its use in creating skin substitutes. A clinical study indicated that biphasic modulated pulsed microcurrent treatment could improve skin appearance. Lastly, research on Wound Induced Hair follicle Neogenesis (WIHN) demonstrated that bacterial presence boosts skin regeneration via IL1R-Myd88 signaling, pointing to a potential therapeutic role of bacteria in skin repair.
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