Serum Granulysin as a Possible Key Marker of the Activity of Alopecia Areata

September 2013 in “ Journal of Dermatological Science ”

Sachiko Ono, Atsushi Otsuka, Yosuke Yamamoto, Tatsuki R. Kataoka, Itsuko Koyanagi, Kenji Kabashima, Kenji Kabashima

serum granulysin alopecia areata acute alopecia areata chronic alopecia areata CD8+ T cells perifollicular lesions allergic disorders AA

Studysummary In this study, researchers found that serum granulysin levels might serve as a novel marker for disease activity in acute alopecia areata, being significantly associated with broader bald skin areas, poorer prognosis, and co-existing allergic disorders.

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