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In this case study, a patient with longstanding androgenetic alopecia and systemic lupus erythematosus showed a positive response to both oral and topical minoxidil after suboptimal outcomes from previous treatments, highlighting the importance of timely diagnosis and management to reduce psychiatric risk factors.

In this study, inducible whole-body Acly-knockout mice revealed that ACLY is essential for skin homeostasis, as its deficiency led to increased sebum production and skin abnormalities, indicating a vital role for cytosolic acetyl-CoA synthesis in preserving skin barrier integrity and systemic lipid regulation.

This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.

This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.

This study found that late-onset systemic lupus erythematosus in a French cohort was characterized by a lower disease severity but reduced survival mainly attributed to aging-related factors.

This review summarizes various indices used to assess disease activity and damage in systemic lupus erythematosus, highlighting challenges in universal consensus and their practical applications in research and clinical settings.

This article reviews how skin manifestations can aid in diagnosing various systemic diseases, focusing primarily on their association with rheumatologic conditions while also addressing vascular, granulomatous, and other disease impacts, aiming to provide dermatologists with practical diagnostic insights.

This case study reported on a 6-year-old boy with Kindler Syndrome born to consanguineous parents, featuring atypical symptoms like hyperpigmented macules and glucose intolerance, contributing to expanding insights into the condition's phenotypic diversity.

In this review, researchers explored how air pollutants increase oxidative stress and inflammation in human skin, affect vitamin D synthesis, and interact with the skin microbiota, also discussing AhR/Nrf2 as a potential target for treating pollution-related skin conditions.

This study proposes a grading system based on comorbidities and systemic involvement to assess the severity of dermatological emergencies.

This case study reports that a woman with systemic lupus erythematosus experienced remission of her symptoms after receiving a combined therapy of corticosteroids and cytostatics.

This study found that Chinese female patients with systemic autoimmune diseases treated intravenously with cyclophosphamide were more likely to experience gastrointestinal discomfort, myelosuppression, and alopecia.

This article discusses approaches to diagnosing and treating androgenetic alopecia but reports no new clinical results.

This review reports that low-dose oral minoxidil can cause hypertrichosis due to increased systemic absorption, and highlights the importance of patient-centered care to manage the psychosocial impacts of this side effect effectively.

This review discusses various hair disorders associated with autoimmune connective tissue diseases, particularly lupus erythematosus, and highlights diagnostic approaches but reports no new clinical results.

Finasteride and minoxidil are effective for hair loss, with potential side effects, and JAK inhibitors show promise for alopecia areata.

This review discusses the role of macrophages in chronic wound healing and suggests that understanding their regulation can inform therapeutic approaches, but it reports no new results.

This review discusses chronic telogen effluvium and diffuse alopecia areata, providing clinical and diagnostic insights, but presents no new clinical findings.

This source reviews a range of sebaceous gland disorders, exploring their clinical characteristics, risk factors, and common treatments, including conditions such as sebaceous gland hyperplasia and acne vulgaris, and highlighting various therapeutic approaches.

This review discusses the relationship between vitamin D and various skin diseases but reports no new clinical results, emphasizing the need to assess and correct vitamin D deficiencies.

In this study, researchers found that mitochondrial complex I plays a crucial role in regulating innate immunity and bone remodeling, with Ndufs4 deletion causing systemic inflammation and osteopetrosis through various metabolic shifts and cellular mechanisms.

This review discusses the role of the endocannabinoid system in skin health and disease, highlighting its potential for future research and applications, but reports no new experimental results.

This review study focused on various in vitro methods to evaluate skin permeation and retention of sunscreens, highlighting the importance of assessing sunscreen penetration due to widespread nanomaterial usage and advancements in cosmetic formulation.

This review explores the role of aging-related changes in skin, discussing how impaired skin barrier function may contribute to systemic inflammation, or "inflamm-aging," which in turn could impact the broader decline in organ and tissue function seen in aged individuals.

This review discusses recent therapeutic approaches for alopecia areata, including the use of Janus kinase inhibitors and interleukin-2, and reports no new clinical results.

This review summarizes recent research on the molecular properties and functions of L-PGDS and PGD2, but reports no new findings, highlighting their pathophysiological roles and guiding future studies.

This study found evidence that atopic dermatitis may increase the risk of developing rheumatoid arthritis, type 1 diabetes, and alopecia areata, but not other autoimmune diseases.

This article discusses the causes, diagnosis, and treatment options for female pattern hair loss, emphasizing the role of topical minoxidil as a primary treatment, but provides no new clinical results.

This review discusses current and emerging therapies for alopecia areata, highlights the challenges in managing this chronic disease, and emphasizes the importance of addressing its psychosocial impacts; it reports no new clinical results.

This study found that using mineralocorticoid receptor antagonists with glucocorticoid therapy improved wound healing in diabetic animals by enhancing keratinocyte proliferation and epithelialization.