6 citations
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November 2024 in “Frontiers in Immunology” This review examines the role of autophagy, specifically macrophage, chaperone-mediated, and microphagy, in the progression of six skin diseases, including psoriasis and systemic lupus erythematosus, illustrating its significance in cellular homeostasis.
6 citations
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March 2023 in “Journal of Ethnopharmacology” In this mouse study, researchers found that the Jieduquyuziyin prescription may lessen lupus-like symptoms and atherosclerosis by inhibiting TLR9/MyD88 signaling and promoting cholesterol efflux.
4 citations
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January 2023 in “Skin health and disease” This study shows that in a mouse model of Alopecia Areata, selective JAK1 inhibition facilitated hair regrowth and inflammation resolution while potentially offering a better safety profile compared to pan-JAK inhibition.
3 citations
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September 2024 in “The FASEB Journal” This review discusses the roles of dermal white adipose tissue in skin functions and pathology, underscoring its antibacterial activity and potential anti-fibrotic role, but reports no new experimental results.
3 citations
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January 2024 in “Liver International” This study by Dr. Manka and colleagues reported that thyroid hormones play a significant role in regulating hepatic stellate cells, influencing liver fibrosis progression via TGFβ signaling. They found that TRα signaling might enhance scar-free tissue regeneration, offering potential pathways for targeted liver fibrosis treatments.
2 citations
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September 2023 in “Cosmetics” This study reviewed existing research on the use of cannabinoids for hair, scalp, and skin conditions, finding moderate evidence for their efficacy in conditions like atopic dermatitis and psoriasis, but noted limited evidence and no standardized guidelines for treatment.
1 citations
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July 2023 in “Journal of Clinical Medicine” This review provides a detailed overview of the causes, prevalence, pathophysiology, clinical presentation, and treatment of beard alopecia, highlighting conditions such as alopecia areata, pseudofolliculitis barbae, and tinea barbae, and aims to serve as a resource for clinicians handling such cases.
1 citations
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January 2023 in “International Journal of Molecular Sciences” This review explores the role of Tregs in autoimmune skin diseases, transplantation, and skin cancer, and discusses Tregs-based therapies' potential for treating autoimmunity without reporting new experimental results.
October 2025 in “Clinical Dermatology Review” This study reports that sildenafil may benefit various dermatological conditions like Raynaud's phenomenon and pressure ulcers, but more research is needed to confirm its efficacy and determine optimal treatment protocols.
August 2025 in “Frontiers in Immunology” This study found that patients with primary cicatricial alopecia are at higher risk of developing various comorbidities, including systemic lupus erythematosus, hypothyroidism, and dermatological conditions, compared to controls.
January 2025 in “Revista Vitae” In this study, researchers found that 2 out of 9 analyzed cosmetic hair growth products contained the banned substance minoxidil, demonstrating the presence of this antihypertensive drug in some cosmetics despite regulations.
March 2024 in “International journal of molecular sciences” This review summarizes current literature associating mitochondrial dysfunction with dermatologic issues like skin aging, hair loss, and poor wound healing, noting potential benefits in targeting mitochondrial components for treatments.
September 2023 in “Gynäkologische Endokrinologie” This review discusses how the hormonal changes of menopause affect skin and hair, highlighting improvements in skin symptoms like dryness and reduced wound healing with estrogen supplementation, and advises healthcare providers to consider broader potential benefits of menopausal hormone therapy when consulting patients.
114 citations
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October 2017 in “American journal of clinical dermatology” Adequate vitamin D is crucial for skin health and should be considered in dermatology.
4 citations
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January 2018 in “Journal of dermatology & dermatologic surgery” This review compares European and U.S. treatment guidelines for hidradenitis suppurativa and reports no definitive standard, highlighting the need for more randomized controlled trials.
April 2026 in “Biomedicines” This study introduces a novel holistic treatment approach for keloid that combines systemic therapies, including Traditional Chinese Medicine, with local interventions to target the inflammatory microenvironment and keloid predisposition for improved management and prevention of recurrence.
January 2024 in “International Journal of Trichology” In this study, researchers reviewed the evidence linking COVID-19 with dermatologic conditions like androgenetic alopecia and concluded that most proposed associations lack convincing statistical support, challenging the idea of these as independent risk factors for COVID-19 severity.
38 citations
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July 2010 in “Clinical, cosmetic and investigational dermatology” This review discusses systemic antifungal treatments for tinea capitis in children, noting that newer agents like terbinafine and itraconazole require shorter courses than the traditional griseofulvin, but may be more costly.
15 citations
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January 2014 in “Anais Brasileiros de Dermatologia” This review discusses the varied cutaneous manifestations of Systemic Lupus Erythematosus and outlines treatment approaches, but it reports no new clinical findings.
July 2018 in “European Medical Journal” This meeting review discusses recent advances in systemic psoriasis treatments, emphasizing the impact of dimethylfumarate monotherapy on understanding psoriasis and treatment strategies; it reports no new clinical results.
3 citations
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July 2012 in “British journal of hospital medicine” This article reviews common hair loss disorders, emphasizing their potential links to systemic disease and the importance of thorough diagnostic evaluation, but reports no new clinical results.
99 citations
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December 2010 in “Journal of The European Academy of Dermatology and Venereology” This article discusses the association of acne with various systemic diseases, emphasizing the role of androgen steroids, insulin resistance, and inflammation in acne pathogenesis, but it reports no new clinical results.
5 citations
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January 2022 in “Proceedings of the Pakistan Academy of Sciences B Life and Environmental Sciences” This review discusses the role of nanoparticles in cancer diagnosis and treatment and outlines their potential to improve outcomes by reducing systemic toxicity and overcoming multidrug resistance, though it reports no new clinical results.
1 citations
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January 2013 in “Elsevier eBooks” The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.
161 citations
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August 2013 in “Journal of experimental botany” This study found that specific ATP-competitive TOR inhibitors (asTORis) decrease root growth in Arabidopsis thaliana in a dose-dependent manner, similar to their effects on mammalian cells.
32 citations
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February 2019 in “Journal of neurochemistry” This study found that pharmacological inhibition of sex steroid synthesis impacts pathogenic processes in traumatic brain injury in a sex-specific manner, with distinct effects of letrozole and finasteride on molecular and neurological outcomes.
32 citations
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June 2012 in “PLoS ONE” This study found that locally injected zalutumumab in healthy volunteers induced a papulopustular rash similar to systemic EGFR inhibitors, and that IL-8 inhibition reduced this dermatological side effect.
21 citations
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April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” This study suggests that gel containing OSF3 loaded in niosomes offers high transfollicular penetration for topical anti-androgenic alopecia treatment with minimal systemic effect.
1 citations
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September 2024 in “IP Indian Journal of Clinical and Experimental Dermatology” This source discusses the potential of topical JAK inhibitors, like tofacitinib, as effective treatments for autoimmune skin diseases, emphasizing their superior safety profile and minimal adverse effects compared to conventional systemic therapies.
March 2026 in “Medeniyet Medical Journal” This study found that hypoxia-conditioned mesenchymal stem cell exosomes increased GM-CSF and decreased IL-1 expression in a dose-dependent manner in a murine model, suggesting potential for treating androgenetic alopecia.