Vitamin D And The Skin: A Review For Dermatologists

March 2019 in “ Actas Dermo-Sifiliográficas ”

Francisco José Navarro‐Triviño, Salvador Arias‐Santiago, Yolanda Gilaberte

Vitamin D dermatology sun exposure antiproliferative properties angiogenesis metastatic capacity neoplasms DNA repair vitamin D receptor cancer systemic corticosteroids osteoporosis skin synthesis

Studysummary This review discusses the relationship between vitamin D and various skin diseases but reports no new clinical results, emphasizing the need to assess and correct vitamin D deficiencies. Our plain-language summary of this paper — not a Tressless recommendation.

The document "Vitamina D y la piel. Una revisión para dermatólogos" from May 2019 discussed the role of Vitamin D in dermatology. Vitamin D can be obtained through diet or sun exposure, with daily requirements varying by age. Deficiency risks include obesity, smoking, insufficient sun exposure, and age. Vitamin D has been shown to have antiproliferative properties, such as inhibiting angiogenesis and the metastatic capacity of some neoplasms, participating in DNA repair, and even the relationship between certain mutations in the vitamin D receptor and cancer. It has been implicated in the pathogenesis and treatment of a variety of dermatological diseases. Chronic use of systemic corticosteroids can lead to complications like osteoporosis, and Vitamin D is fundamental in dermatology, not only because its synthesis occurs in the skin, but also due to its multiple actions reflected in different diseases where it seems to be involved.

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9 / 9 results

research Vitamin D and the Skin: An Update for Dermatologists

114 citations , October 2017 in “American journal of clinical dermatology”

Adequate vitamin D is crucial for skin health and should be considered in dermatology.

research The Role of Micronutrients in Alopecia Areata: A Review

63 citations , May 2017 in “American Journal of Clinical Dermatology”

This review found that patients with alopecia areata may have lower levels of vitamin D, zinc, and folate, but conflicting evidence precludes definitive clinical recommendations for micronutrient supplementation.

research Efficacy and Safety of Topical Calcipotriol in Management of Alopecia Areata: A Pilot Study

39 citations , January 2017 in “Dermatologic Therapy”

This study found that topical calcipotriol lotion resulted in hair regrowth in 59.1% of alopecia areata patients, with better response observed in those with lower serum vitamin D levels.

research Estimated Serum Vitamin D Status, Vitamin D Intake, and Risk of Incident Alopecia Areata Among US Women

23 citations , September 2016 in “Archives of Dermatological Research”

This study found no significant association between vitamin D intake or estimated vitamin D status and the risk of developing alopecia areata among women.

research Extraskeletal Actions of Vitamin D

119 citations , July 2016 in “Annals of the New York Academy of Sciences”

This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.

research Hidradenitis Suppurativa/Acne Inversa: An Endocrine Skin Disorder?

41 citations , June 2016 in “Reviews in endocrine and metabolic disorders”

This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.

research Vitamin D Deficiency in Alopecia Areata

105 citations , March 2014 in “British journal of dermatology/British journal of dermatology, Supplement”

In this study, patients with alopecia areata were found to have significantly lower serum vitamin D levels compared to those with vitiligo and healthy individuals, with lower levels correlating with increased disease severity.

research Reduced Level of 25-Hydroxyvitamin D in Chronic/Relapsing Alopecia Areata

40 citations , April 2013 in “Dermato-endocrinology”

In this study, researchers observed vitamin D insufficiency in many patients with Alopecia Areata, suggesting its potential role in managing this autoimmune condition.

research Successful Treatment of Alopecia Areata with Topical Calcipotriol

51 citations , January 2012 in “Annals of dermatology/Annals of Dermatology”

This case report describes a 7-year-old boy with alopecia areata and reduced vitamin D receptor expression whose condition improved after using calcipotriol, a strong vitamin D analog.