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December 2025 in “International Journal of Molecular Sciences” This study reported that atelocollagen enhances collagen synthesis and reduces oxidative stress in aged skin by increasing glycine uptake through GlyT1, resulting in improved skin elasticity and collagen density in aged mice, with effects superior to glycine alone.
November 2025 in “Frontiers in Pharmacology” This study observed that both in vitro and in vivo research demonstrated rice bran extract can significantly enhance collagen and elastin synthesis, reduce water loss, and improve skin quality and elasticity, highlighting its potential as a sustainable cosmetic ingredient.
June 2025 in “Materials Today Bio” In this study, a silk fibroin hydrogel containing recombinant NT3 was found to promote scar-less wound healing in a mouse skin injury model by enhancing type III collagen expression and inducing hair follicle formation.
January 2011 in “Padua Research Archive (University of Padua)” This study suggests that human skin locally synthesizes active sex steroid hormones, impacting inflammation, cell behavior, and wound healing, with potential implications for therapies in aging and impaired wound recovery.
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February 2009 in “PLoS ONE” This study found that the enzyme glutamine synthetase is distributed throughout the epidermis and its activity in keratinocytes is notably increased by ammonium ions, suggesting the skin serves as a reservoir for glutamine generation.