Hair Disorders Associated with Autoimmune Connective Tissue Diseases

    October 2014 in “ PubMed
    Nicoletta Cassano, Paolo Amerio, Francesco Domenico D’Ovidio, Gino Antonio Veña
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    TLDR Autoimmune diseases like lupus, dermatomyositis, and scleroderma can cause hair loss and other hair problems, and treatments for these diseases might also affect hair.
    The document from 2014 reviewed hair disorders associated with autoimmune connective tissue diseases (CTDs). These disorders often manifest as various clinical patterns, including telogen hair loss, diffuse thinning or fragility of hair, and scarring alopecia. Less common hair disorders include anagen effluvium, alopecia areata, and trichomegaly. Lupus erythematosus (LE), dermatomyositis (DM), and scleroderma were identified as diseases with a predilection for hair disorders. Alopecia was found to be a significant sign in the course of LE, especially systemic LE. In DM, scalp involvement was common, often characterized by a diffuse, violaceous, scaly, non-scarring, and symptomatic hair loss. The most important variant of scarring alopecia in the context of CTDs was associated with discoid lupus erythematosus (DLE). The document also noted that some drugs used to treat CTDs could cause hair loss or hyperthrichosis.
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