Hair Disorders Associated with Autoimmune Connective Tissue Diseases
October 2014
in “
PubMed
”
telogen hair loss diffuse thinning fragility of hair scarring alopecia anagen effluvium alopecia areata trichomegaly lupus erythematosus dermatomyositis scleroderma systemic lupus erythematosus discoid lupus erythematosus hyperthrichosis telogen effluvium hair thinning hair fragility scarring hair loss anagen hair loss patchy hair loss excessive hair growth LE DM SLE DLE
TLDR Autoimmune diseases like lupus, dermatomyositis, and scleroderma can cause hair loss and other hair problems, and treatments for these diseases might also affect hair.
The document from 2014 reviewed hair disorders associated with autoimmune connective tissue diseases (CTDs). These disorders often manifest as various clinical patterns, including telogen hair loss, diffuse thinning or fragility of hair, and scarring alopecia. Less common hair disorders include anagen effluvium, alopecia areata, and trichomegaly. Lupus erythematosus (LE), dermatomyositis (DM), and scleroderma were identified as diseases with a predilection for hair disorders. Alopecia was found to be a significant sign in the course of LE, especially systemic LE. In DM, scalp involvement was common, often characterized by a diffuse, violaceous, scaly, non-scarring, and symptomatic hair loss. The most important variant of scarring alopecia in the context of CTDs was associated with discoid lupus erythematosus (DLE). The document also noted that some drugs used to treat CTDs could cause hair loss or hyperthrichosis.