Skin Manifestations Associated With Systemic Diseases – Part I

The document provides a comprehensive review of skin manifestations associated with systemic diseases, focusing on conditions like Lupus Erythematosus (LE), Dermatomyositis (DM), Rheumatoid Arthritis (RA), and various granulomatous diseases. In LE, skin lesions can range from benign to severe, sometimes fatal eruptions. DM is an inflammatory disease with various cutaneous manifestations, and its skin lesions' clinical course may not parallel that of muscle disease. RA is an autoimmune disease associated with inflammation and joint deformities, with lesions suggestive of the disease. The document also discusses conditions like palisaded granulomatous dermatitis, Felty’s syndrome, Still’s disease, Raynaud’s phenomenon, Sjogren’s syndrome, scleroderma, and Sweet’s syndrome, each with their unique skin manifestations. Other conditions like Behçet’s disease, Bowel-associated dermatosis-arthritis syndrome (BADAS), Pyoderma gangrenosum, Erythema elevatum diutinum, and various forms of vasculitis are also covered. The document emphasizes the importance of early diagnosis to minimize potential complications.