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A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

Epigenetic mechanisms control skin development by regulating gene expression.

Foxn1 is important for fat development, metabolism, and wound healing in skin.

The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.

Discoid Lupus Erythematosus causes scalp plaques that can lead to hair loss, and antimalarial drugs are effective treatments.

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

The scalp's microorganisms significantly affect hair health and disease.

The new matrix improves skin regeneration and graft performance.

Desmoglein 4 is controlled by specific proteins that affect hair growth.

Runx3 helps determine hair shape.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

A mouse gene mutation increases the risk of skin cancer.

Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

Hair follicles help attract immune cells to the skin during stress.

Overexpressing follistatin in mice delays wound healing and reduces scar size.

Hair growth and development are controlled by specific signaling pathways.

Wounded skin cells can revert to stem cells and help heal.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.

Hairless protein can block vitamin D activation in skin cells.

The project created a standardized system for classifying skin lesions in lab rats and mice.