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Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.

Essential oils may improve dogs' health and melatonin can help with their sleep and anxiety, but both should be used carefully.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.