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The compound 4c effectively inhibits the enzyme linked to hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Four-amino acid part makes enzyme sensitive to finasteride.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.