Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the identification and roles of different epidermal stem cell types in skin homeostasis and repair, and reports no new experimental findings.

This review discusses hair follicle stem cells for wound healing and reports no new clinical results, noting their potential but emphasizing the need for further understanding and safety in clinical applications.

This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.

This study found that Pep-1-mediated mitochondrial transplantation was as effective as PRP therapy in restoring hair loss related to aging in mice, with distinct improvements in hair and skin-related measures.

This study found that a blackcurrant extract with phytoestrogen activity increased hair number and stem cell marker expression in a menopausal rat model, suggesting a potential benefit for hair loss.

In this study, one type of commercial culture medium supported expression of stem cell markers in hair follicle epithelial stem cells, but their differentiation potential and hair follicle-inducing ability declined over time.

This study found that the M5 isolation method for human dermal papilla cells significantly improved attachment efficiency, proliferative capacity, and trichogenic potential, providing an optimized strategy for scalable manufacturing in hair regeneration therapies for conditions like alopecia.

This study reports that myoepithelial cells in submucosal glands can act as reserve stem cells, regenerating surface airway epithelium after severe injury through a mechanism involving Sox9 and Wnt signaling.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

This study found that WNT10A is significantly upregulated in human esophageal squamous cell carcinoma and is associated with enhanced tumor cell migration, invasion, and poor survival.

In this study, dermal papilla cells from rat vibrissae showed potential for treating CNS injuries by secreting neurotrophic factors and promoting neuronal differentiation more effectively than bone marrow mesenchymal stem cells.

This study found that activating Toll-like receptor 3 in periodontal ligament stem cells enhanced their stem cell and immunosuppressive properties, potentially supporting effective periodontal tissue regeneration.

This study developed a new melanocyte cultivation medium without chemical mitogens, melanogenesis enhancers, or bovine products, demonstrating successful proliferation and melanotic differentiation of human melanocytes from hair follicles.

The study found that over-expressing ornithine decarboxylase in the outer root sheath of the hair follicle in mice increases UVB-induced tumor growth and invasive squamous cell carcinoma compared to inter-follicular epidermal keratinocytes.

This study found that dermal stem cells from granulation tissue promoted wound healing and reduced fibrosis in a combined radiation and skin wound mouse model.

In this study, hypoxic conditions were found to enhance stemness in hair follicle neural crest stem cells, while inhibiting the Hippo pathway significantly decreased their proliferation.

This study established an efficient short-term culture system for human hair follicle stem cells using human fibronectin and ROCK inhibitor Y-27632, enhancing cell proliferation and stemness for potential applications in hair follicle tissue engineering.

This study found that melatonin may enhance goat cashmere growth by activating Wnt signaling and regulating stem cell pluripotency through mechanisms involving NOGGIN and BMP4 pathways.

This study found that quercetin significantly promoted proliferation and inhibited apoptosis of hair follicle stem cells from Arbas cashmere goats, suggesting potential benefits for improving cashmere production.

In this study, researchers discovered that HEY2+ dermal papilla cells exhibit stemness and contribute to dermal regeneration during wound healing, as shown by the expression of a reporter gene in regenerated dermal cells of tamoxifen-induced transgenic mice.

This study found that Shi-Bi-Man significantly promotes hair regeneration in cynomolgus monkeys by increasing hair follicle stem cells and up-regulating metabolic pathways.

In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.

This research observed that overexpression of lncRNA H19 in human dermal papilla cells inhibited cell senescence and maintained hair follicle-inducing abilities by activating the Wnt signaling pathway, suggesting potential therapeutic strategies for androgenetic alopecia.

This study found that using a microwell array device to expand hair follicle stem cells in Matrigel significantly increased cell numbers and enhanced hair regeneration in mice.

This study identified a subpopulation of neural crest-derived progenitor cells in human corneal endothelial tissue from normal and Fuchs endothelial corneal dystrophy donors, which may have potential for future cell therapy development.

In this study, researchers used transcriptomics and modeling to uncover previously unknown cell populations and marker genes in developing hair follicles, providing insights into early cell fate establishment and offering tools for further research on skin appendages.

This study found that human hematopoietic mesenchymal stem cells increased the viability and migration of human outer root sheath cells in an in vitro alopecia areata model, involving Wnt/β-catenin and JAK/STAT pathways.

This study found that stimulating dermal papilla cells with specific adipo-osteogenic factors and growth factors helped maintain their viability and restored their hair-forming activity in vitro.

This study used an ex vivo human skin model to show that tropical conditions disrupt skin homeostasis, resulting in epidermal thickening and junctional flattening, and found that Kombucha tea extract may help preserve skin structure under such stress.

In this study, porcine collagen acellular dermal matrix scaffolds combined with mice platelet-rich plasma were associated with increased hair density and follicle regeneration in mice with alopecia, suggesting a potential therapeutic approach.