TLDR Quercetin can boost hair follicle stem cell growth in cashmere goats, potentially improving cashmere quality.
This study explores the impact of quercetin on secondary hair follicle stem cells (SHFSCs) in Arbas cashmere goats, highlighting its potential to enhance cashmere production. Quercetin, known for its antioxidant and anti-inflammatory properties, was found to promote SHFSC proliferation and inhibit apoptosis, with an optimal concentration of 10 μg/mL for 48 hours. It increased the expression of proliferation markers like PCNA and TERT, improved mitochondrial function, reduced oxidative stress, and influenced key signaling pathways such as PI3K–Akt, Wnt, and TGF-β. These findings suggest quercetin's potential to improve cashmere quality by modulating SHFSC activity, although further in vivo studies are needed for validation.
2 citations
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February 2022 in “Genomics” Researchers discovered new cell types in goat hair follicles that could help understand hair regrowth and human hair loss.
8 citations
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July 2020 in “BMC genomics” The research found genes that change during cashmere goat hair growth and could help determine the best time to harvest cashmere.
1 citations
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August 2019 in “Research Square (Research Square)” Cashmere goats have a hair growth cycle with specific genes regulating growth, regression, and resting periods.
50 citations
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March 2018 in “BMC Genomics” Non-coding RNAs help control hair growth cycles in cashmere goats, suggesting ways to improve cashmere production.
14 citations
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January 2015 in “Genetics and molecular research” The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.
61 citations
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April 2013 in “PloS one” The study found key genes and pathways involved in cashmere goat hair growth stages.
22 citations
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July 2012 in “Journal of integrative agriculture/Journal of Integrative Agriculture” Hoxc13 is linked to seasonal hair growth in Cashmere goats and is affected by melatonin.
