research Implication of MicroRNA Regulation in Para-Phenylenediamine-Induced Cell Death and Senescence in Normal Human Hair Dermal Papilla Cells
Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.
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570-600 / 1000+ resultsresearch Heterogeneity in the Genetic Alterations and Clinical Presentation of Acrodermatitis Enteropathica: Case Report and Literature Review
AE can have varied symptoms and genetic causes, but zinc therapy helps.
research Activation of the Integrated Stress Response in Human Hair Follicles
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
research Molecular Pathology of Skin Adnexal Tumors
New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
research Hair Growth-Promoting Mechanisms of Red Ginseng Extract Through Stimulating Dermal Papilla Cell Proliferation and Enhancing Skin Health
Red Ginseng Extract helps hair grow and improves skin health by stimulating cell growth and enhancing the body's antioxidant defense system.
research Ultraviolet-Induced Red Fluorescence in Androgenetic Alopecia Indicating Alterations in Microbial Composition
Red fluorescence in AGA scalps is linked to different microbes.
research In Vitro Strategies for Mimicking Dynamic Cell–ECM Reciprocity in 3D Culture Models
The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
research Topical Application of Anti-Cancer Drug Bortezomib Stimulates Proliferation of Follicular Cells and Induces Expression of Hair Keratins via GATA-3 Transcription Factor
Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.
research Differential Expression of mTOR Signaling Pathway Proteins in Lichen Planopilaris and Frontal Fibrosing Alopecia
The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.
research The Role of Mitochondria in the Non-Targeted Effect of Ionizing Radiation
Mitochondria may influence how cells respond to radiation, affecting nearby non-irradiated cells.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research The Human Skin Microbiome in Selected Cutaneous Diseases
Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
research Mutational Landscape of Extramammary Paget Disease
The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research Regulatory T Cells in Inflammatory Skin Disease: From Mice to Humans
Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
research CD98hc (SLC3A2) Regulation of Skin Homeostasis Wanes With Age
CD98hc's role in skin health decreases with age.
research MicroRNA in Skin Diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Immunopathology of the Human Hair Follicle
The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
research Structure and Development of the Skin and Cutaneous Appendages
Understanding skin structure and development helps diagnose and treat skin disorders.
research Buschke-Ollendorff Syndrome: Clinical Features and Genetic Insights
Buschke-Ollendorff syndrome is a rare genetic disorder causing skin and bone changes, with some cases also showing ADHD or developmental delays.
research Chromatin Architectural Protein CTCF Controls Epidermal Barrier Formation, Hair Follicle Fate Maintenance, and Suppresses Inflammatory Responses in the Skin Epithelium
The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research The Effect of JAK Inhibitor on Survival, Anagen Re-Entry, and Hair Follicle Immune Privilege Restoration in Human Dermal Papilla Cells
Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.
research Perspectives in Dermatopathology: Telomeres and Telomerase in Aging and Cancer with Emphasis on Cutaneous Disease
Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
research Next-Generation Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling
ILK is essential for skin development, pigmentation, and healing.
research Keratin-Mediated Hair Growth and Its Underlying Biological Mechanism
Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
research CD201+ Fascia Progenitors Choreograph Injury Repair
CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.
research Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition
Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.