research Simultaneous Determination of Multi-Class Active Pharmaceutical Ingredients by UHPLC-HRMS
A new method was developed to accurately detect and measure 47 different drug ingredients in various products.
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research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
research Acne and Acneiform Eruptions
Early treatment of acne is crucial to prevent scarring and psychological effects.
research Nutraceutical Intervention of Seeds in the Treatment of Polycystic Ovarian Syndrome: A Systematic Review
Eating certain seeds may help reduce symptoms of Polycystic Ovary Syndrome.
research Risk of Estrogen-Driven Malignancies in Females on 5-Alpha Reductase Inhibitors
Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.
research Tumor Necrosis Factor Inhibitors and Janus Kinase Inhibitors in the Treatment of Cicatricial Alopecia: A Systematic Review
Tofacitinib and adalimumab are promising treatments for cicatricial alopecia with few side effects.
research Signaling Pathways and Targeted Therapeutic Strategies for Polycystic Ovary Syndrome
Effective PCOS treatments require targeting specific signaling pathways.
research Clinico-Trichoscopic Evaluation of Hirsutism Treated With Intense Pulsed Light in a Tertiary Care Hospital in Eastern India
Intense Pulsed Light is an effective and safe hair removal method for people with excessive hair growth.
research Ageratum Conyzoides L. Extract Inhibits 5α-Reductase Gene Expression and Prostaglandin D2 Release in Human Hair Dermal Papilla Cells and Improves Symptoms of Hair Loss in Healthy Males and Females in an Open Label Pilot Study
Ageratum conyzoides L. extract may effectively and safely treat hair loss.
research Management of Teenagers with Polycystic Ovarian Syndrome
The document concludes that personalized treatment, including lifestyle changes and medication, is essential for managing PCOS in teenagers, while also addressing their psychological well-being.
research The First Visit: Consultation and Workup Before Sperm Banking
A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.
research Polycystic Ovary Syndrome: Symptoms, Risks, and Treatments
PCOS treatment should address both symptoms and metabolic risks, starting with lifestyle changes and possibly including medication.
research Toxicity of the Pharmaceuticals Finasteride and Melengestrol Acetate to Benthic Invertebrates
Finasteride harms invertebrates' survival and burial ability.
research Heat-Treated Limosilactobacillus Fermentum LM1020 with Menthol, Salicylic Acid, and Panthenol Promotes Hair Growth and Regulates Scalp Microbiome Balance in Androgenetic Alopecia: A Double-Blind, Randomized, and Placebo-Controlled Clinical Trial
Heat-treated Limosilactobacillus fermentum with menthol, salicylic acid, and panthenol promotes hair growth and balances scalp microbiome in people with androgenetic alopecia.
research Clinical Use of Extracellular Vesicles in the Management of Male and Female Pattern Hair Loss: A Preliminary Retrospective Institutional Review Board Safety and Efficacy Study
Extracellular vesicles may effectively treat hair loss with minimal side effects.
research Roles of Steroid Receptors in the Lung and COVID-19
Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
research Safety and Tolerability of Low-Dose Oral Minoxidil in Adolescents: A Retrospective Review
The safety and tolerability of low-dose oral minoxidil for treating hair loss in adolescents is not clearly determined.
research What You Need to Know About Gender-Affirming Healthcare
The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.
research Assessing Medication Use Patterns Among Patients With Polycystic Ovary Syndrome at a Tertiary Care Teaching Hospital in South Korea: A Retrospective Study
Most patients with PCOS were prescribed medroxyprogesterone acetate or oral contraceptives, with some experiencing side effects or needing prescription changes.
research Oral Supplementation with L-Cystine, Serenoa Repens, Cucurbita Pepo, and Pygeum Africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, Placebo-Controlled, Randomized Clinical Study
The supplement significantly improves hair density and appearance in people with hair loss.
research Therapeutic Maintenance Effect of Finasteride 1 Mg Every Other Month Regimen in Androgenetic Alopecia: A Prospective Cohort Study
Taking finasteride every other month can still help with hair loss but may be less effective over time compared to taking it daily.
research The Impact of Gender Affirming Hormone Therapy on Physical Performance
Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.
research Effect of Gender-Affirming Hormone Therapy on Hair Growth: A Systematic Review of the Literature
Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.
research Prediction of Therapeutic Outcomes of Female Pattern Hair Loss Patients Based on Clinical Features with Application of Artificial Intelligence
Artificial intelligence can accurately predict hair growth and treatment results in female pattern hair loss patients, with age of onset and duration being key factors.
research Saccharomyces Cerevisiae BLYAS, A New Bioluminescent Bioreporter For Detection Of Androgenic Compounds
The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.
research Depositing Alpha-Mangostin Nanoparticles to Sebaceous Gland Area for Acne Treatment
α-mangostin nanoparticles improved acne with minimal irritation.
research Common Skin Disorders in Pediatric Skin of Color
Children with darker skin tones can have specific skin conditions that need tailored treatments.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research A Retrospective Analysis of Efficacy and Safety of Intralesional Triamcinolone Injections in the Treatment of Frontal Fibrosing Alopecia as Monotherapy or Concomitant Therapy
Intralesional triamcinolone injections can effectively stop frontal fibrosing alopecia with minimal side effects.
research The Protease Corin Regulates Electrolyte Homeostasis in Eccrine Sweat Glands
Corin helps control salt and sweat release in sweat glands.