Assessing Medication Use Patterns Among Patients With Polycystic Ovary Syndrome at a Tertiary Care Teaching Hospital in South Korea: A Retrospective Study

August 2024 in “ Medicine ”

Jihye Yu, Mi Kyung Moon, Hyo‐Jeong Ahn, Yong-June Yang

polycystic ovary syndrome PCOS medroxyprogesterone acetate MPA oral contraceptives oligomenorrhea amenorrhea birth control pills

TLDR Most patients with PCOS were prescribed medroxyprogesterone acetate or oral contraceptives, with some experiencing side effects or needing prescription changes.

This retrospective study of 212 PCOS patients at a South Korean tertiary care hospital found that medroxyprogesterone acetate (MPA) and oral contraceptives (OCs) were the most commonly prescribed medications. MPA was used for its benefits on insulin sensitivity and lipid profiles, while OCs were used to manage menstrual irregularities, hirsutism, and acne. 21.2% of patients changed their prescriptions due to side effects or lack of effectiveness, and 7.1% reported adverse drug events. The study underscores the need for personalized treatment approaches and highlights the role of pharmacists in optimizing medication adherence and treatment plans.

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Research cited in this study

9 / 9 results

Efficacy and Safety of Anti-Androgens in the Management of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

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