TLDR Early intervention and tailored management can reduce skin side effects from cancer treatments.
The ESMO Clinical Practice Guidelines provided recommendations for preventing and managing dermatological toxicities associated with anticancer agents, such as acneiform rash, hand-foot syndrome, alopecia, pruritus, paronychia, and onycholysis. Dermatological adverse events (AEs) were common in cancer patients undergoing systemic therapies, with targeted therapies causing AEs in 75%-90% of patients and immunotherapies in ≥30%. The guidelines emphasized preventive measures, such as skin care and the use of oral tetracyclines, and therapeutic strategies, including topical and systemic corticosteroids. For chemotherapy-induced alopecia (CIA), scalp cooling was the only method shown to prevent it, with 50%-65% efficacy, and minoxidil 5% was suggested for hair regrowth post-chemotherapy. The guidelines highlighted the importance of early intervention and tailored management strategies to mitigate these side effects and maintain treatment efficacy and quality of life for patients.
53 citations,
April 2018 in “Journal of The American Academy of Dermatology” Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.
67 citations,
April 2018 in “JAMA Dermatology” Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.
141 citations,
September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
149 citations,
January 2015 in “Journal of the American Academy of Dermatology” Targeted cancer therapies often cause skin side effects, needing dermatologist care.
48 citations,
September 2013 in “Oncologist” Endocrine therapies for cancer significantly increase the risk of hair loss.
218 citations,
January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
76 citations,
August 2007 in “Supportive care in cancer” Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.
3 citations,
November 2018 in “Oncology issues” Cancer survivors often experience worse skin problems from treatment than expected, and working with dermatologists could help improve their condition.
7 citations,
May 2014 in “Clinical practice” Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.
2 citations,
October 2018 in “Springer eBooks” Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.
1 citations,
July 2023 in “Journal of Clinical Medicine” Different causes of beard hair loss have various treatments, including medications, lifestyle changes, and procedures to stimulate hair growth.
2 citations,
October 2016 Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.
