TLDR Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.
The study investigated the prevalence and impact of dermatological side effects from chemotherapy in 91 women with advanced cancers. It found that 86.8% of patients experienced skin, nail, and hair side effects, with 75.8% developing hair loss, 23.1% experiencing nail changes, and 18.7% developing palmo-plantar erythrodysesthesia (PPE). These side effects significantly affected patients' quality of life, with skin changes being the most frequently reported unpleasant side effect. The study concluded that dermatological side effects from chemotherapy were common and had a major impact on quality of life, highlighting the need for patient counseling and consideration of side effect profiles when planning chemotherapy regimens.
14 citations,
October 2003 in “Annals of Oncology” About half the patients treated with capecitabine and docetaxel developed severe hand-foot syndrome.
522 citations,
January 2001 in “Cancer investigation” Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
275 citations,
March 1999 in “Journal of The American Academy of Dermatology” Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.
86 citations,
November 2020 in “Annals of Oncology” Early intervention and tailored management can reduce skin side effects from cancer treatments.
2 citations,
October 2016 Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.
2 citations,
October 2018 in “Springer eBooks” Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.
1 citations,
January 2015 in “Springer eBooks” Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.
141 citations,
September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
