Chemotherapy-Induced Dermatological Toxicity: Frequencies and Impact on Quality of Life in Women’s Cancers. Results of a Prospective Study

August 2007 in “ Supportive care in cancer ”

Mark Hackbarth, Norbert Haas, Christina Fotopoulou, W. Lichtenegger, Jalid Sehouli

chemotherapy hair loss dermatological toxicity skin side effects nail changes palmo-plantar erythrodysesthesia PPE

TLDR Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.

The study investigated the prevalence and impact of dermatological side effects from chemotherapy in 91 women with advanced cancers. It found that 86.8% of patients experienced skin, nail, and hair side effects, with 75.8% developing hair loss, 23.1% experiencing nail changes, and 18.7% developing palmo-plantar erythrodysesthesia (PPE). These side effects significantly affected patients' quality of life, with skin changes being the most frequently reported unpleasant side effect. The study concluded that dermatological side effects from chemotherapy were common and had a major impact on quality of life, highlighting the need for patient counseling and consideration of side effect profiles when planning chemotherapy regimens.

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Chemotherapy-Induced Dermatological Toxicity: Frequencies and Impact on Quality of Life in Women’s Cancers. Results of a Prospective Study

Research cited in this study

research High Incidence of Severe Hand-Foot Syndrome During Capecitabine-Docetaxel Combination Chemotherapy

research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy

research Mucocutaneous Reactions to Chemotherapy

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