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Glossary Skin Side Effects

adverse skin reactions from medications or treatments

Skin side effects refer to adverse reactions that occur on the skin as a result of medications, treatments, or underlying health conditions. These can range from mild issues like dryness and rashes to more severe conditions such as blistering, peeling, or changes in pigmentation. For example, certain chemotherapy drugs can cause skin reactions like redness, itching, or even more serious conditions like Stevens-Johnson syndrome. Understanding these side effects is crucial for both patients and healthcare providers to manage and mitigate discomfort and potential complications.

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Research

5 / 1000+ results

research Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails

179 citations , October 2018 in “American Journal of Clinical Dermatology”

This review outlines various dermatologic adverse events associated with targeted therapies and immunotherapies, emphasizing the need for collaboration between dermatologists and oncologists to manage these effects effectively; it reports no new clinical findings.

research Alemtuzumab-Induced Secondary Autoimmune Skin Disorders as Side Effects of Multiple Sclerosis Therapy: Problem That Can Be Influenced or Fate? A Narrative Overview of The Literature A Neuroprotective Role of Vitamin D?

January 2022 in “Medical research archives”

This article reviews the potential role of vitamin D supplementation as an adjunct to alemtuzumab therapy in multiple sclerosis management, noting its possible benefits for autoimmune comorbidities and patient adherence, but reports no new clinical results.

research Classification and management of skin, hair, nail and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors

138 citations , February 2007 in “European journal of cancer”

This review discusses the classification, pathogenesis, and management of skin, hair, nail, and mucosal changes due to EGFR inhibitors, emphasizing the importance of informing patients to improve therapy compliance.

research [Reactions and side effects of ovulation inhibitors on the skin].

January 1978 in “PubMed”

This study reviewed various dermatological conditions associated with oral contraceptive use, highlighting increased pigmentation, decreased sebum production, and changes in hair growth, among other effects.

research Chemotherapy and the Skin: Understanding Dermatologic Side Effects

February 2026 in “Cureus”

This study reported that chemotherapy-induced skin reactions in cancer patients are mostly mild to moderate and manageable with supportive care, suggesting that early dermatologic intervention can improve patient outcomes without interrupting chemotherapy.

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Learn

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learn Melatonin

Can melatonin cause side effects on the skin or hair? No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.

learn Clascoterone

Does clascoterone have any side effects? Most reported side effects of clascoterone are skin irritation, but the acne-cream label also warns of stress-hormone (HPA-axis) suppression and raised potassium in some patients.

learn GHK-Cu

GHK-Cu: Does it have side effects or is it completely safe? For topical cosmetic use, one 24-hour study in cultured skin cells found a low potential for irritation, but no clinical trial has characterised its side effects on the scalp. Injected or oral GHK-Cu has no published human safety data, and the FDA lists injectable GHK-Cu among compounding substances that may present significant safety risks.

learn Rapamycin

Are there any visible side effects when using rapamycin cream or serum on the scalp? No study has tested rapamycin on the scalp; in facial trials skin reactions were common (64% vs 29% placebo; Aitken et al. 2023, PMID 37463422).

learn white tea

Are there any side effects or scalp reactions associated with white tea in hair treatments? In one trial, women using green-tea cream plus capsules reported more skin irritation than placebo; a US cosmetic safety panel judged tea-leaf ingredients safe as used only when formulated not to cause allergy.

learn Peppermint

herb and oil thought to stimulate skin and hair

learn Tretinoin

Vitamin A retinoid cream, prescribed for acne

learn Bimatoprost

Prostaglandin eye drop used for glaucoma and eyelash growth

learn Microneedling

Technique that makes tiny punctures in the scalp with fine needles

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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Community Join

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community Experiencing Side Effects After 6 Months on Finasteride - Continue or Stop?

in General 137 upvotes 1 year ago

The user experienced positive hair growth with finasteride but developed gut issues, dry skin, thinning eyebrows, fatigue, low libido, and erection difficulties after stopping it. They are seeking advice on whether to resume finasteride or stay off it to recover.

community Side effects of topical azelaic acid?

4 upvotes 5 years ago

Azelaic acid is considered a strong DHT inhibitor with no reported sexual side effects, making it a potential alternative for those who cannot use finasteride. It can be used with minoxidil, but may cause skin irritation.

community Did you notice any other positive effect while on finasteride/dutasteride?

in Finasteride/Dutasteride 66 upvotes 1 year ago

Finasteride and dutasteride can stop hair loss and improve skin, with some users experiencing increased libido and harder erections. However, some report side effects like softer erections and brain fog.

community Stop the fear mongering of oral minoxidil its one of the best treatments available in 2020. It does not cause heart lesions or adverse cardiac effects like people claim. I am maintaining with just oral minoxidil with retrograde alopecia and diffuse thinning all over nw3 hairline

78 upvotes 6 years ago

Oral minoxidil is considered a safe and effective treatment for hair loss at low dosages, with minimal cardiac risks. Users report positive results, though some experience side effects like increased heart rate and skin changes, and consulting a doctor is advised.

community Skin Aging and Minox

5 upvotes 11 years ago

The conversation is about concerns over skin aging from using minoxidil for hair loss, with the user planning to use a minimal amount to avoid side effects. Other users suggest that overuse may cause temporary skin dryness but not actual aging, and emphasize proper application.

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Clinics

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Experts

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SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin