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Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.

Lower levels of certain genes in hair cells improve hair loss treatment outcomes.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Hair follicle stem cells are promising for blood vessel formation and tissue repair.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.

Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Fat cells are important for tissue repair and stem cell support in various body parts.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Metabolic signals and cell shape influence how cells develop and change.

Human dermal stem cells can become functional skin pigment cells.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Minoxidil treatment improves heart defects in a DiGeorge syndrome model.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Mouse stem cells from hair follicles can improve wound healing and reduce scarring.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Fibroblast Growth Factor-9 helps repair heart damage after a heart attack by creating new blood vessels, especially in diabetics.

PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Bead-jet printing of stem cells improves muscle and hair regeneration.