Bead-Jet Printing Enabled Sparse Mesenchymal Stem Cell Patterning Augments Skeletal Muscle and Hair Follicle Regeneration

December 2022 in “ Nature Communications ”

Yuanxiong Cao, Jiayi Tan, Haoran Zhao, Ting Deng, Yunxia Hu, Junhong Zeng, Jiawei Li, Yifan Cheng, Jiyuan Tang, Zhiwei Hu, Keer Hu, Bing Xu, Zitian Wang, Yaojiong Wu, Peter E. Lobie, Shaohua Ma

mesenchymal stem cells MSC hair follicle regeneration Matrigel beads PI3K-Akt signaling pathway Wnt/β-CATENIN signaling pathway skin healing tissue regeneration stem cells hair regeneration Matrigel PI3K-Akt Wnt signaling skin repair

Studysummary This study found that a new "bead-jet" printing system for mesenchymal stem cells in Matrigel beads improved skeletal muscle regeneration and skin healing in a high-density, sparse pattern.

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