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In this study, the researchers developed a living microecological hydrogel containing Chlorella and Bacillus subtilis that showed potential in promoting the healing of infected diabetic wounds by providing continuous oxygen delivery and anti-infective properties.

This study found that adding keratin to a collagen hydrogel improved keratinocyte differentiation compared to a pure collagen hydrogel, particularly when calcium was also present in the media.

This review discusses the biofunctionalization of hydrogel scaffolds for vascular tissue regeneration and reports promising results from in vivo studies, such as improved angiogenesis and healing in pressure ulcers when using specific peptides.

In this study, researchers developed a silk fibroin-based hydrogel with added curcumin and pluronic F127, which displayed antibacterial properties against Methicillin-resistant Staphylococcus aureus and showed potential for skin tissue regeneration, without cytotoxicity.

In this study, researchers developed a self-assembling hydrogel called RADA-PDGF2 and found it to accelerate wound closure in a mouse model due to its pro-proliferative and pro-migratory properties, without causing cytotoxicity or immunogenicity.

In this study, researchers investigated the penetration and cellular responses to nanoplastics in human skin models with compromised barriers, finding that nanoplastics can penetrate the skin, accumulate in cells, and trigger inflammatory responses through specific signaling pathways.

This review reports that sodium alginate-based hydrogels show promise in biomedical applications due to their biocompatibility and versatility, but challenges such as mechanical strength and stability remain, highlighting the need for continued research to facilitate their clinical transition.

This review discusses how functionalized hydrogels can modulate the microbiome to aid tissue regeneration and infection control, highlighting their potential to deliver therapeutic agents effectively and support beneficial immune responses.

This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.

In a study using female Wistar rats, the researchers found that a liquid allantoin-enriched pectin hydrogel significantly improved wound healing, achieving a 71.43% reduction in healing time and complete wound closure in 15 days.

In this study, researchers developed a multifunctional hydrogel for wound healing, incorporating antibacterial and antioxidant properties that demonstrated significant inflammation reduction and tissue regeneration in animal models, with high antibacterial efficacy against E. coli and S. aureus.

In this study, an injectable self-healing bioactive nanoglass hydrogel showed promise for repairing normal and MRSA-infected skin wounds by inhibiting bacterial growth and reducing inflammation.

This study evaluated a new carboxymethyl chitosan/polyaldehyde dextran (CMCS/PD) hydrogel and found it to be a promising tissue adhesive for trauma emergencies in rats, showing rapid gel formation, strong adhesion, and better antibacterial properties than some commercial alternatives.

In this study, phage-containing hydrogels were shown to effectively treat wounds infected with E. faecalis by promoting wound healing through controlled phage release, suggesting potential to improve clinical outcomes for such infections.

This study demonstrated that gelatine-based hydrogel foams loaded with platelet extracellular vesicles (pEVs) promoted full wound closure in a chronic wound rat model within 14 days, suggesting potential for personalized treatment of chronic diabetic wounds.

Photobiomodulation did not significantly improve hair density in dogs with alopecia X.

Cyclosporin A and FK506 can start new hair growth in mice, but ascomycin and rapamycin cannot.

This review discusses the growing importance of hydrogel scaffolds in skin wound healing, highlighting their unique properties and recent advancements in their use for treating difficult tissue damage, particularly within tissue engineering.

This review discusses the unique properties, design, and fabrication of peptide hydrogels for biomedical applications, focusing on advances in drug delivery, gene therapy, and regenerative medicine; it reports no new clinical results.

In this study, researchers reviewed the progress and challenges in using hydrogels for 3D printing in biomedical applications, highlighting advancements in structural complexity, and identifying ongoing issues like resolution improvement, cell viability, and ethical concerns for clinical use.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential for disease treatment, but notes challenges in their clinical application.

This study developed granular hydrogels with reversible interparticle cross-linking, finding they offer high mechanical stability and enhance cell recruitment, making them promising for injectable and 3D printable scaffolds in tissue engineering and therapeutic delivery.

This study developed a zinc-infused egg white and GelMA hydrogel that enhanced cellular processes crucial for wound healing, including fibroblast proliferation and collagen expression, and demonstrated promising biocompatibility and bioactivity in vivo, suggesting potential effectiveness in repairing damaged tissues.

This review explores how combining extracellular vesicles with hydrogels and utilizing 3D bioprinting technologies creates innovative composite systems for wound healing, offering advanced mechanical and biological support, while addressing challenges like degradation and regulatory issues in clinical applications.

This study reported that a novel hydrogel wound dressing, created using a Brachybotrys paridiformis polysaccharide derivative and chitosan, significantly accelerated wound healing and tissue regeneration in vivo, showing nearly complete healing by day 15 compared to controls.

This review discusses recent findings on cellular antioxidant responses to oxidative stress and their implications for treating various human diseases but reports no new clinical results.

This review highlights advancements in nanoemulgel platforms for topical and transdermal drug delivery, noting their improved safety and efficacy over conventional treatments in in vitro and in vivo studies, specifically for conditions like skin diseases and inflammatory issues.

This study focused on developing agarose/fucoidan hydrogels for the encapsulation of pancreatic cells, reporting that these materials supported cell viability and self-organization into pseudo-islets over 7 days, highlighting potential for diabetes treatment applications.

This review highlights how integrating medicinal chemistry with delivery science could transform the limitations of PROTACs—such as poor solubility and low cell permeability—into strengths, potentially advancing these compounds from experimental stages to clinical applications by optimizing their delivery and enhancing therapeutic efficacy.

The researchers reported that sulfated chitosan-containing sponges can modulate macrophage activity in diabetic wounds, reducing inflammation and promoting angiogenesis and tissue regeneration, which may enhance wound healing outcomes.