A Facile and Biocompatible Hydrogel Based on Oxidized Brachybotrys Paridiformis Polysaccharide for Enhanced Wound Healing

    March 2026 in “ ACS Omega ”
    Na Zou, Jie Zhou, Xifan Mei, Qing Chen, Sitong Wu
    Studysummary This study reported that a novel hydrogel wound dressing, created using a <i>Brachybotrys paridiformis</i> polysaccharide derivative and chitosan, significantly accelerated wound healing and tissue regeneration in vivo, showing nearly complete healing by day 15 compared to controls.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The study developed a hydrogel wound dressing using oxidized Brachybotrys paridiformis polysaccharide (OBPP) and O-carboxymethyl chitosan (CMCS), which demonstrated excellent biocompatibility and enhanced wound healing capabilities. The hydrogel promoted human umbilical vein endothelial cells migration and showed superior in vivo wound-healing performance, with the hydrogel-treated group achieving significantly smaller wound areas by day 9 (7.59 ± 1.83%) compared to the control group (44.14 ± 18.22%). By day 15, the hydrogel group exhibited nearly complete healing with smooth, scab-free skin, highlighting its potential as an effective wound dressing.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results