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Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Endocannabinoids help control mast cell activity in human skin.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Postinflammatory hyperpigmentation causes dark skin patches and needs personalized treatment.

Microneedling is promising for treating various skin issues but needs more research to confirm its effectiveness and safety.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Fullerenes show potential in skin care but need more safety research.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Scientists created stem cells that can grow hair and skin.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.

The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Mannosylerythritol lipids are good for skin and hair care products.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.