Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages

    April 2014 in “ Journal of Investigative Dermatology ”
    Veronika Mlitz, Bettina Strasser, Karin Jaeger … Leopold Eckhart
    Studysummary This study identified a new S100 fused-type protein, scaffoldin, in reptiles and birds and suggests that SFTP-positive epithelia serve as scaffolds for the growth of various skin appendages, indicating a common evolutionary origin.
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    Research cited in this study 5

    1. Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans American journal of human genetics · 2009
    2. Identification of Reptilian Genes Encoding Hair Keratin-Like Proteins Suggests a New Scenario for the Evolutionary Origin of Hair Proceedings of the National Academy of Sciences · 2008
    3. Embryonic Keratinization in Vertebrates in Relation to Land Colonization Acta Zoologica · 2008
    4. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    5. Trichohyalin, an Intermediate Filament-Associated Protein of the Hair Follicle ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986

    Related research 1

    1. Solid Basal Cell Epithelioma Possibly Originates From the Outer Root Sheath of the Hair Follicle PubMed · 1993