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    Glossary Skin Development

    process by which skin forms and matures from embryonic stages

    Skin development refers to the process by which the skin forms and matures from embryonic stages through to adulthood. This involves the differentiation of various cell types, such as keratinocytes, melanocytes, and fibroblasts, and the formation of distinct layers like the epidermis, dermis, and hypodermis. Proper skin development is crucial for creating a functional barrier that protects the body from environmental hazards and regulates temperature and hydration.

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    1. 1358 PRC1 fine-tunes gene repression and activation to safeguard skin epithelium development and stem cell specification Journal of Investigative Dermatology · 2018 · 1 citations
    2. Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids Cell Reports · 2018 · 169 citations
    3. Skin Cell Heterogeneity in Development, Wound Healing, and Cancer Trends in cell biology · 2018 · 211 citations
    4. Progress in the Development of Stem Cell-Derived Cell-Free Therapies for Skin Aging Clinical Cosmetic and Investigational Dermatology · 2023 · 22 citations
    5. Development, Characterization, and Use of a Fetal Skin Cell Bank for Tissue Engineering in Wound Healing Cell Transplantation · 2006 · 71 citations
    6. Hair follicle stem cell progeny heal blisters while pausing skin development bioRxiv (Cold Spring Harbor Laboratory) · 2020
    7. Hair follicle stem cell progeny heal blisters while pausing skin development EMBO reports · 2021 · 10 citations
    8. Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin Journal of Investigative Dermatology · 2024 · 6 citations
    9. Methotrexate-associated lymphoproliferative disorder: Sequential development of angioimmunoblastic T-cell lymphoma-like lymphoproliferation in the lymph nodes and diffuse large B-cell lymphoma in the skin in the same patient European Journal of Dermatology · 2015 · 6 citations
    10. 1439 Development of a complex skin organ in human induced pluripotent stem cell-derived organoids 2023
    11. Single-cell chromatin landscapes of mouse skin development Scientific Data · 2022 · 2 citations
    12. Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach Journal of Tissue Engineering · 2024
    13. Dendritic cell migrations involving the pilosebaceous unit in the development of murine skin Zoological Journal of the Linnean Society · 1980 · 7 citations
    14. Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration Biomaterials · 2024 · 25 citations
    15. CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata Journal of Immunology · 2016 · 64 citations
    16. Protein Kinase Cε, which Sensitizes Skin to Sun's UV Radiation–Induced Cutaneous Damage and Development of Squamous Cell Carcinomas, Associates with Stat3 Cancer Research · 2007 · 76 citations
    17. Growth Factors, Cell-Cell and Cell-Matrix Interactions in Skin during Follicle Development and Growth 1988 · 11 citations
    18. BMP signaling in the control of skin development and hair follicle growth Differentiation · 2004 · 165 citations
    19. A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    20. 1365 Elf5, a novel regulator of skin stem/progenitor cells fate during skin development? 2023
    21. The Role of ATP-dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity Stem cell biology and regenerative medicine · 2018
    22. MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway Journal of Cell Biology · 2014 · 103 citations
    23. Differential expression of a gene homologous to a G-α protein gene in neonatal mouse skin during development of hair follicles Journal of dermatological science · 2001 · 5 citations
    24. Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration Cell Reports · 2023 · 44 citations
    25. 10×Genomics Single-cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Related Potentially to the Fineness of Cashmere Fiber Research Square (Research Square) · 2020 · 1 citations
    26. A multi-omic single-cell landscape of perinatal mouse skin maps lineage specification and reveals shared dynamics in human fetal skin Experimental & Molecular Medicine · 2026
    27. Wnt Signaling in Skin Development, Homeostasis, and Disease Cold Spring Harbor Perspectives in Biology · 2012 · 260 citations
    28. Apoptosis in human skin development: Morphogenesis, periderm, and stem cells Developmental dynamics · 1994 · 253 citations
    29. 1397 LSD1 is critical for epidermal development and skin barrier formation Journal of Investigative Dermatology · 2023
    30. The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development The EMBO Journal · 2007 · 125 citations