Human Epidermal Transglutaminase: Enzyme Crucial for Epidermal Terminal Differentiation

    June 1983 in “ Journal of Investigative Dermatology ”
    Lowell A. Goldsmith
    Studysummary This study reports that human epidermal transglutaminase activity increases with treatment using organic solvents and chemicals without significant molecular weight changes, which may allow modulation of the enzyme in skin diseases.
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    Research cited in this study 5

    1. Human Epidermal Transglutaminase: Preparation and Properties Journal of Biological Chemistry · 1976
    2. Vertebral Epidermal Transamidases Biochimica et Biophysica Acta (BBA) - Protein Structure · 1974
    3. Formation of the Iε-(γ-Glutamyl)Lysine Crosslink in Hair Proteins: Investigation of Transamidases in Hair Follicles Biochemistry · 1972
    4. The Occurrence of the ε-(γ-Glutamyl)Lysine Cross-Link in the Medulla of Hair and Quill Biochimica et Biophysica Acta (BBA) - Protein Structure · 1972
    5. Iε-(γ-Glutamyl) Lysine Cross-Linkage in Citrulline-Containing Protein Fractions From Hair Biochemistry · 1971