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    Glossary Epidermal Differentiation

    process where skin cells mature to form protective barrier

    Epidermal differentiation is the process by which cells in the outermost layer of the skin, called the epidermis, mature and change to form a protective barrier. This involves the transformation of basal cells into specialized cells like keratinocytes, which produce keratin, a protein that helps protect the skin from environmental damage. This process is crucial for maintaining skin integrity and function.

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    1. Autophagy-Mediated Cellular Remodeling during Terminal Differentiation of Keratinocytes in the Epidermis and Skin Appendages Cells · 2024 · 7 citations
    2. Chapter 3 Expression and Modification of Keratins During Terminal Differentiation of Mammalian Epidermis 1987 · 81 citations
    3. 591 Chromatin architectural protein CTCF regulates terminal keratinocyte differentiation in the developing epidermis and hair follicles 2021
    4. Colocalization of Cystatin M/E and its Target Proteases Suggests a Role in Terminal Differentiation of Human Hair Follicle and Nail 2008 · 22 citations
    5. Characterization of Mouse Profilaggrin: Evidence for Nuclear Engulfment and Translocation of the Profilaggrin B-Domain during Epidermal Differentiation 2002 · 25 citations
    6. A function for Rac1 in the terminal differentiation and pigmentation of hair Journal of cell science · 2012 · 11 citations
    7. The role of cathepsin E in terminal differentiation of keratinocytes Biological Chemistry · 2011 · 15 citations
    8. Human Epidermal Transglutaminase Journal of Investigative Dermatology · 1983 · 53 citations
    9. AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    10. The Process of Cornification Evolved From the Initial Keratinization in the Epidermis and Epidermal Derivatives of Vertebrates: A New Synthesis and the Case of Sauropsids International review of cell and molecular biology · 2016 · 73 citations
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