Retinoic Acid-Induced Epidermal Transdifferentiation in Skin
June 2014
in “
Journal of developmental biology
”
retinoic acid epidermal transdifferentiation embryonic skin epithelial-mesenchymal interactions Gbx1 Tgm2 TGF-β2 hair follicle formation Wnt/β-catenin pathway transcription factors skin morphogenesis skin differentiation therapeutic applications hair loss RA skin transformation skin development skin therapy
Studysummary This study found that retinoic acid induces epidermal transdifferentiation into mucosal epithelium in both chick and mammalian embryonic skin, involving specific gene expressions and pathways.
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