The Role of MEK and Antizyme in Keratinocyte Stem Cell Expansion and Differentiation

    April 2012 in “ Cancer Research ”
    Theresa D. Carr, David J. Feith, Lisa M. Shantz
    Studysummary This study found that overexpression of antizyme in MEK-activated transgenic mice reduced skin tumor development and restored normal differentiation of keratinocyte progenitor cells, highlighting the role of polyamines in keratinocyte biology.
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