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Targeting CXXC5 and GSK-3β may help treat male pattern baldness.

Nanoparticles may improve treatment for lung disease by targeting cells better and reducing side effects.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

A new topical treatment using SAMiRNA technology shows promise in increasing hair growth for androgenetic alopecia.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Both mouse and rat models are effective for testing alopecia areata treatments.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Porcine acellular dermal matrix treatment helps wounds heal faster and reduces scarring by affecting Jag1 in skin stem cells.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

Inducing ferroptosis in hepatic stellate cells is crucial for treating liver fibrosis.

Lipids may help treat hair loss by promoting hair growth through the HIF-1 pathway.

Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Activating Nrf2 can help protect against hearing loss.

Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

A3B5 can reduce skin pigmentation and slow melanoma growth.

Kidney cancer cells without folliculin are more sensitive to radiation due to increased self-eating cell death.

Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.