Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections

    January 2021 in “ Parkinsonism & related disorders (Online)/Parkinsonism & related disorders ”
    Nicki Niemann, Andrew Billnitzer, Joseph Jankovic
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    TLDR Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.
    The document from January 1, 2021, discusses the connection between Parkinson's disease and various skin disorders. It categorizes these disorders into non-iatrogenic, such as melanoma, seborrheic dermatitis, sweating disorders, bullous pemphigoid, and rosacea, and iatrogenic, which are side effects from Parkinson's medications or their delivery systems, including drugs like carbidopa/levodopa and procedures like deep brain stimulation. The study highlights the significance of α-synuclein in peripheral tissues like the skin and the use of induced pluripotent stem cells from skin fibroblasts for understanding Parkinson's pathogenesis, drug development, stem cell therapies, and diagnostics.
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