Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections

The document from January 1, 2021, discusses the connection between Parkinson's disease and various skin disorders. It categorizes these disorders into non-iatrogenic, such as melanoma, seborrheic dermatitis, sweating disorders, bullous pemphigoid, and rosacea, and iatrogenic, which are side effects from Parkinson's medications or their delivery systems, including drugs like carbidopa/levodopa and procedures like deep brain stimulation. The study highlights the significance of α-synuclein in peripheral tissues like the skin and the use of induced pluripotent stem cells from skin fibroblasts for understanding Parkinson's pathogenesis, drug development, stem cell therapies, and diagnostics.