Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections

    Nicki Niemann, Andrew Billnitzer, Joseph Jankovic
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    Studysummary This article reviews skin disorders in Parkinson's disease, highlighting the potential of skin studies and stem cell research to advance understanding and treatment of the neurodegenerative disorder, without presenting new results.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The document from January 1, 2021, discusses the connection between Parkinson's disease and various skin disorders. It categorizes these disorders into non-iatrogenic, such as melanoma, seborrheic dermatitis, sweating disorders, bullous pemphigoid, and rosacea, and iatrogenic, which are side effects from Parkinson's medications or their delivery systems, including drugs like carbidopa/levodopa and procedures like deep brain stimulation. The study highlights the significance of α-synuclein in peripheral tissues like the skin and the use of induced pluripotent stem cells from skin fibroblasts for understanding Parkinson's pathogenesis, drug development, stem cell therapies, and diagnostics.
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