29 citations
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January 2020 in “BioMed Research International” This study found that sinapic acid promotes the browning of 3T3-L1 adipocytes and may offer therapeutic potential for obesity by influencing mitochondrial biogenesis through the p38 MAPK/CREB signaling pathway.
25 citations
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March 2017 in “Archives of Dermatological Research” This study suggests that sinapic acid may promote hair growth in human hair follicle dermal papilla cells by activating specific signaling pathways and inducing the expression of growth factors.
5 citations
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November 2017 in “Asian Journal of Beauty and Cosmetology” This study found that sinapic acid demonstrated antioxidant and anti-inflammatory effects against UVB-induced damage in human keratinocytes, suggesting its potential as an anti-aging cosmetic ingredient.
This study observed that a combination of sinapic acid and glabridin from Zhimo herbal extract improved hair growth and reduced oxidative stress in a DHT-induced model of androgenetic alopecia in mice by preventing ferroptosis and stabilizing β-Catenin, offering potential application for AGA treatment.
February 2026 in “Molecules” This study reported that a novel nanomedicine combining berberine and sinapic acid significantly inhibited the growth of mouse mammary carcinoma cells and demonstrated an anti-tumor effect in vivo, without significant systemic toxicity after 28 days, suggesting a promising, low-toxicity therapeutic strategy for breast cancer.
January 2024 in “International Journal of Pharmacognosy and Pharmaceutical Research” This review highlights the potential of plant-derived molecules like Epigallocatechin-3-Gallate and Ginsenosides to promote healthy hair growth by enhancing nutrient supply and blood flow to the scalp, and notes their growing role in natural hair care product development.
16 citations
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April 2022 in “Journal of Food Quality” This study found that blueberry waste in Australia has high phenolic content and antioxidant potential, suggesting potential uses in food, pharmaceutical, and nutraceutical industries.
July 2025 in “Food Safety and Health” This study used metabolomics to identify distinctive metabolic and phenolic profiles in American ginseng (Panax quinquefolius) from various regions, revealing specific biomarkers that can help differentiate between ginseng from Northeast China, Shandong, and the United States.
5 citations
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October 2024 in “International Journal of Molecular Sciences” This study observed that piperonylic acid activated key signaling pathways in dermal papilla cells and increased hair growth markers, and a clinical trial showed users of a piperonylic acid formulation had more hair than those using a placebo, suggesting its potential for treating hair loss.
5 citations
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September 2020 in “Molecules” In this study, extracts from three Polynesian plants—Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana—were found to increase dermal papilla cell proliferation and modulate hair growth-related gene expression, suggesting potential for stimulating hair growth.
5 citations
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June 2018 in “Records of Natural Products” This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.
21 citations
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June 2022 in “Molecules” This review discusses the phytochemistry and pharmacological activities of Perilla frutescens, detailing its bioactive compounds and their potential health benefits, but reports no new clinical results.
12 citations
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June 2024 in “Nutrients” In this review, researchers highlighted that natural polyphenolics like flavonoids and resveratrol may help enhance testosterone production in aging males by boosting the expression of the Star gene in Leydig cells, potentially preventing age-related degenerative conditions linked to testosterone insufficiency.
5 citations
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January 2025 in “Pharmaceuticals” This review highlights the potential of Coffea arabica as an active ingredient in skincare, noting its bioactive compounds from leaves and beans show promising anticellulite, anti-inflammatory, antioxidant, and anti-aging properties, with unique phenolic concentrations in leaves offering enhanced skin benefits.
February 2026 in “International Journal of Molecular Sciences” This study investigated the photoprotective properties of Brazilian pepper tree extract against UV-induced damage in skin cells, reporting that it enhanced expression of genes relevant to skin health and showed superior activity compared to standard antioxidants.
February 2025 in “Applied Sciences” This study found that extracts from heterotropic cultures of Scenedesmus deserticola JD052 enhanced hair-inductive properties in human dermal papilla cells more effectively than photoautotrophic extracts, likely through activation of AKT/β-catenin signaling, despite similar loliolide content.
In this study, aqueous and aqueous-alcoholic extracts of Ajuga reptans showed promising hepatoprotective and wound-healing properties, with significant effects observed in experimental models, suggesting potential for development into official medicinal products pending further research.
In this open-label study, the researchers observed that using Kerascalp hair serum daily for 90 days improved hair thickness, density, and strength while reducing hair loss in subjects with mild to moderate androgenetic alopecia, with benefits persisting even after discontinuation.
2 citations
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May 2025 in “Antioxidants” This study examined the phytochemicals and antioxidant activities of methanolic extracts from Cameroonian Prunus africana bark and Leea indica and Paullinia pinnata leaves, identifying various phenolic compounds and significant antioxidant properties through multiple assays.
9 citations
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November 2022 in “Applied sciences” This review explores marine algae-derived phenolic compounds and their potential cosmeceutical benefits, but reports no new clinical results.
1 citations
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August 2025 in “Seeds” This review examines the potential of Cucurbitaceae seeds, such as those from watermelon, melon, and pumpkin, as sustainable and innovative ingredients in cosmetics, highlighting their rich bioactive composition and benefits for skin and hair, despite challenges like environmental instability and low permeability.
15 citations
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January 2021 in “Cellular and Molecular Biology” This study found that Prosopis farcta is a rich source of phenolic compounds with strong antioxidant activity, suggesting its potential for use in food, beverage, feed, and pharmaceutical applications.
January 2026 in “Food and Feed Research” This review highlights the traditional medicinal uses, phytochemical composition, and pharmacological properties of Musa paradisiaca, noting its applications in treating diarrhea and other conditions, and identifying key bioactive compounds with antimicrobial, antioxidant, and other bioactivities through in vitro and in vivo studies.
7 citations
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May 2024 in “Molecules” In this study, red rice was found to contain 87.2% carbohydrates, 9.1% proteins, and demonstrated bioactive properties due to its flavan-3-ol phenolic compounds, suggesting potential health benefits beyond its nutritional content.
70 citations
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May 2023 in “Molecules” This source reviews recent research on Ginkgo biloba, highlighting its medicinal benefits due to compounds in the leaves and concerns over toxic alkylphenols in seeds. It also discusses patents for its food production uses and ongoing studies on toxicity and drug interactions.
2 citations
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October 2023 in “JURNAL ILMU KEFARMASIAN INDONESIA” In this study, researchers formulated a nanosuspension of kenikir leaf extract that meets physical criteria and exhibits cytotoxic activity against MCF-7 breast cancer cells.
60 citations
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June 2017 in “IOSR Journal of Pharmacy (IOSRPHR)” This review highlights the chemical components and various potential health effects of Daucus carota but reports no new experimental results.
54 citations
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May 2017 in “Biomedicine & Pharmacotherapy” This review discusses the nutrient profile and potential health benefits of pumpkin and watermelon seeds, concluding they are underutilized and could be developed into various nutraceuticals.
1 citations
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September 2024 in “African Journal of Biomedical Research” This review highlights the therapeutic potential of Curcuma longa and Dalbergia sissoo, noting their antioxidant, anti-inflammatory, and anticancer activities, but emphasizes the lack of studies on their combined effects and suggests future research could enhance therapeutic outcomes.
April 2026 in “Journal of Microbiology Biotechnology and Food Sciences” This study found that Carthamus caeruleus (L.) leaf extracts possess higher antioxidant and antibacterial activities compared to rhizome extracts, and are rich in phenolic and flavonoid compounds, suggesting potential use as a natural therapeutic agent.