1 citations
,
February 2024 in “Pharmacognosy Journal” In this study, fenugreek seed extract showed significant androgenic and spermatogenic effects in male rats, likely through inhibiting testosterone metabolism, without impacting cardiovascular health.
1 citations
,
April 2023 in “Preprints.org” This study found that the guided SEFFI technique for facial volume restoration and anti-aging is minimally invasive with a low complication rate, suggesting it as a promising treatment option.
3 citations
,
August 2022 in “Pharmaceuticals” This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.
3 citations
,
April 2016 in “Research and reports in urology” In a cell-free test setting, this study found that a novel saw palmetto extract effectively inhibited the 5α-reductase type II enzyme, showing promising bioactivity comparable to finasteride for promoting prostate health.
22 citations
,
December 2020 in “mSphere” This study identified a fungal sulfotransferase enzyme, FgSULT1, from *Fusarium graminearum*, expanding the sulfotransferase superfamily and offering new biocatalytic methods for producing bioactive sulfates.
55 citations
,
June 2007 in “Journal of Statistical Planning and Inference” This study introduces an extended approach to the Bonferroni procedure that accounts for correlations among endpoints, aiming to improve test power while maintaining strong control of the family-wise type I error rate in clinical trials.
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This abstract discusses the FitSpresso weight loss supplement's potential benefits and mechanisms but provides no clinical research findings; it reports on its ingredients and consumer ratings instead.
56 citations
,
September 2013 in “Experimental Dermatology” This guide reviews the biology of sebaceous glands and their evaluation methods, emphasizing their roles beyond lipid production in skin health and disease, and reports no new research results.
26 citations
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December 2015 in “Journal of The European Academy of Dermatology and Venereology” This article introduces a new grading system called the FPHL Severity Index to better identify and monitor early stages of female pattern hair loss using clinical criteria.
7 citations
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October 2017 in “Artificial Cells Nanomedicine and Biotechnology” This research observed that finasteride-loaded ethosomes showed improved permeation across rat skin and human cadaver scalp skin compared to unencapsulated finasteride, potentially enhancing delivery to hair follicle units.
April 2014 in “The FASEB Journal” This study found that Geranium Sibiricum L extract may promote hair growth by increasing cell proliferation and migration while modulating cytokine expression in human dermal papilla cells under stress conditions.
7 citations
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March 2023 in “European Journal of Dermatology” Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
1 citations
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November 2023 in “Contact dermatitis” In this study, sensitization to ethylhexyl salicylate was found in 27.3% of patients with frontal fibrosing alopecia, suggesting it may be a potential contact allergen for this condition.
2 citations
,
April 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that a novel saw palmetto supercritical CO2 extract effectively inhibits 5α-reductase type II in vitro, suggesting its potential for promoting prostate health in benign prostatic hyperplasia.
November 2024 in “International Journal of Applied Pharmaceutics” This study found that a fenugreek seed extract nanoformulation significantly improved hair growth and length in Wistar rats with alopecia, outperforming conventional gels and oils, suggesting enhanced skin penetration and reduced side effects.
20 citations
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September 2015 in “Protein expression and purification” This study demonstrated that safflower seeds can be engineered to express oleosin-FGF10, which showed a dose-dependent effect on cellular proliferation, potentially facilitating scalable protein production.
March 2025 in “Skin Appendage Disorders” In this study, selenium disulfide shampoo was found to reduce dandruff severity and rebalance the scalp microbiome in individuals with all hair types experiencing moderate to severe dandruff, with subjects reporting high satisfaction and good tolerance over a 6-week period.
39 citations
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November 2015 in “Nanomedicine” This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.
June 2014 in “Journal of biomedical research” This study found that ethanol extract and an ethyl acetate fraction of Sargassum fusiforme promoted hair regrowth in C57BL/6 mice and stimulated expression of hair growth-related genes in both in vitro and in vivo models.
November 2005 in “CRC Press eBooks” This article reviews the development and challenges of skin penetration enhancers, highlighting their limitations in compatibility and safety, and reports no new clinical findings.
August 2026 in “Fabad Journal of Pharmaceutical Sciences” This study developed a Neusilin® US2-based solid self-nanoemulsifying drug delivery system for finasteride that showed improved stability and drug delivery, with complete dissolution comparable to standard Propecia® tablets.
July 2018 in “European Medical Journal” This meeting review discusses recent advances in systemic psoriasis treatments, emphasizing the impact of dimethylfumarate monotherapy on understanding psoriasis and treatment strategies; it reports no new clinical results.
3 citations
,
September 2018 in “Current Drug Delivery” This study found that a finasteride topical gel formulation using propylene glycol and Tween® 80 showed significantly enhanced permeation compared to a control formulation without these enhancers.
11 citations
,
October 2014 in “Gene” In this study, researchers characterized the FGF5 gene in Chinese Merino sheep, identified a new mRNA splicing variant, FGF5S, and noted its restricted expression in the brain, spleen, and skin.
8 citations
,
March 2022 in “Journal of The Taiwan Institute of Chemical Engineers” This study found that fucoidan extracts from Sargassum glaucescens, particularly oligo-fucoidans, promoted hair growth and increased related gene expression in human dermal papilla cells and mice models.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that sebaceous gland atrophy in psoriatic lesions correlates with the down-regulation of specific lipid biosynthetic gene modules, potentially affecting hair appearance without damaging follicles.
April 2017 in “Journal of Investigative Dermatology” This study found that fisetin, a dietary flavonoid, significantly improved psoriasiform skin lesions in mice by promoting cell differentiation, inhibiting proliferation, and modulating inflammatory responses.
4 citations
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November 2017 in “PubMed” This study found that Synsepalum dulcificum seed oil hair treatment significantly reduced hair breakage and improved hair health indices in women, outperforming both placebo and argan oil treatments.
September 2024 in “Journal of the American Academy of Dermatology” This introduction highlights that a common challenge with managing dandruff, a mild form of seborrheic dermatitis, is compliance with treatment, and notes that selenium disulfide shampoo is beneficial for this condition.
51 citations
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September 2020 in “Nucleic Acids Research” This article introduces signatureSearch, a software package designed for gene expression signature searching and functional enrichment analysis, but reports no new clinical results.