A Selenium Disulfide-Based Shampoo Is Beneficial For Dandruff Management And Rebalancing The Scalp Microbiome Of Subjects Of Any Hair Type

    March 2025 in “ Skin Appendage Disorders ”
    Pascal Reygagne, Claire Deloche-Bensmaine, Stéphanie Leclerc‐Mercier, Julien Fauré, Natalia Kovylkina, Cécile Clavaud, Audrey Guéniche, Victoria Barbosa
    TLDR Selenium disulfide shampoo effectively reduces dandruff and improves scalp health for all hair types.
    A 6-week study involving 93 adults with various hair types demonstrated that selenium disulfide (SeS2) shampoo effectively manages moderate-to-severe dandruff and rebalances the scalp microbiome. Participants, predominantly women and of European and African origin, applied the shampoo twice weekly. Significant improvements were observed in dandruff severity, erythema, and itching across different hair types, with all p-values <0.05. The SeS2 shampoo was well tolerated and highly appreciated by the subjects, confirming its benefits for dandruff management and scalp health.
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