May 2025 in “Health Science Reports” This study reported that applying Serum WS Biotin, a water-soluble form of D-Biotin, daily for 3 months significantly reduced hair shedding and increased hair strength in volunteers with moderate to excessive hair shedding, while showing good skin compatibility.
62 citations
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September 2014 in “PLoS ONE” This study identified distinct human and bacterial protein profiles in sebaceous follicular casts, with acne samples showing proteins linked to inflammation and normal samples showing proteins involved in stress protection.
June 2024 in “Institutional Repository of the Federal Technological University of Paraná (RIUT) (Federal University of Technology – Paraná)” This study assessed Mapu Cosméticos' business plan for producing castor bean-derived products, projecting a net profit from year two and indicating financial feasibility with a favorable Net Present Value and Internal Rate of Return.
3 citations
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January 2016 in “Annals of Dermatology” This article discusses the multifactorial nature of acne, including its association with follicular hyperkeratosis, sebaceous lipids, Propionibacterium acnes, and perifollicular inflammation, but reports no new clinical findings.
April 2017 in “Journal of Investigative Dermatology” In this study, bovine milk-derived oligosaccharides were found to increase sebocyte proliferation, lipid content, and inflammatory mediator synthesis through the mTORC1 pathway, potentially contributing to milk-based inflammation in sebocytes.
7 citations
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April 2021 in “Journal of advanced pharmaceutical technology & research” This study reported that compound 16 (olean-12-en-3beta-ol, cinnamate) from Merremia peltata showed potential as an androgen receptor antagonist, suggesting it may benefit alopecia treatment based on molecular docking and ADME-Tox predictions.
1 citations
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January 1998 in “Cosmetics and toiletries” Both amodimethicone and dimethicone copolyol amine are effective hair conditioners.
August 2019 in “Key engineering materials” This study found that Carthamus tinctorius floret extract, at a concentration of 0.05 mg/mL, significantly inhibited 5α-reductase activity in DU-145 cells more effectively than standard treatments finasteride and dutasteride, with a stable microemulsion formulation enhancing its skin permeation and stability.
18 citations
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July 2009 in “Drug Metabolism and Disposition” This study identified previously unknown phase I and phase II metabolites of finasteride in human bile and urine using a specialized bile collection technique and advanced mass spectrometry analysis.
8 citations
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July 1977 in “Lipids” This study found a negative correlation between dietary monoene levels, particularly oleic acid, and the capacity for PGE₂ synthesis in rat skin, with the most severe skin issues noted in those fed Zephyr rapeseed oil.
1 citations
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January 2019 This study found that a hair tonic combining fragrant pandan and celery extracts increased hair length in guinea pigs, with the 1:5 concentration showing the best growth activity.
1 citations
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August 2025 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” BMI should be considered in future research on dutasteride's effects on fertility.
15 citations
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October 2006 in “Journal of the American Academy of Dermatology” This case report describes subcutaneous emphysema in a patient's forearm as a rare complication of liquid nitrogen spray used on hypertrophic actinic keratosis, resolving spontaneously within a day.
6 citations
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September 2019 in “Journal of cosmetic dermatology” This study found that lower serum melatonin levels were associated with increased skin aging grades among individuals in Ulaanbaatar, suggesting melatonin loss may contribute to earlier skin aging.
January 2024 in “Jurnal Ilmu Kesehatan Hewan” In this veterinary case report, a mixed breed dog with Malassezia dermatitis showed significant improvement and hair regrowth after 28 days of treatment with ketoconazole and other supportive therapies.
18 citations
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March 2010 in “Therapeutic Drug Monitoring” This study developed a faster method to analyze fatty acid ethyl esters in human hair, potentially distinguishing alcohol consumption levels more efficiently.
8 citations
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October 1998 in “Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology” Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
This study found that isolated human scalp hair follicles express PGE2 genes and EP2 protein, suggesting PGE2 may play a crucial role in regulating hair growth.
July 2024 in “Revista Científica de Estética e Cosmetologia” This study aimed to develop a dermocosmetic exfoliating formulation using babassu fibers for androgenetic alopecia treatment, but found that although the formulation met sensory standards, it was unstable in sunlight and heat, suggesting a need for optimization before commercialization.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study developed a novel hydrogel combining Chlorella extracellular polysaccharide–selenium nanoparticles (EPS-SeNPs) with biocompatible components, which demonstrated strong antibacterial and anti-inflammatory effects, significantly accelerating wound healing in an infected rat model, and enabling pH-based monitoring of healing.
July 2013 in “Pharmaceutical Regulatory Affairs Open Access” This study reported that invasomes, utilizing limonene as a component, enhanced the transdermal permeation of finasteride by over 21 times, indicating their potential as a novel drug delivery system.
4 citations
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July 2022 in “International Journal of Cosmetic Science” This study found that the moisture sorption and desorption process can differentiate between cosmetic treatments of hair and provide insights into hair fibre structure changes, with bleaching causing greater symmetry breaking than perming.
April 2018 in “Journal of Investigative Dermatology” This study demonstrated that in genetic mouse models, the calcium sensor Stim1, not Stim2, is essential for sweat secretion in sweat glands.
May 2010 in “International Journal of Cosmetic Science” This study found that reduced hair samples showed higher protease degradation than permed hair, which increased with repetitive perming, and degradation was influenced by the type of mercaptan used.
3 citations
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July 2003 in “PubMed” This study found that laser-based goniophotometry can effectively monitor changes in hair surface reflection related to color and cuticle cell tilt across different ethnic origins.
10 citations
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June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
1 citations
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April 2022 in “Acta histochemica” This study found that oral pumpkin seed oil increased hair follicle proliferation in mice without causing liver toxicity, unlike finasteride and minoxidil which showed adverse effects.
April 2020 in “Journal of the Endocrine Society” This study suggests that hair cortisol measurement could serve as an alternative diagnostic method for Cushing’s disease, showing acceptable concordance with urinary free cortisol despite differing evaluated periods.
In a study on female Wistar rats, researchers found that a hair tonic containing a 7.5%:2% combination of talok and pare leaf extracts increased hair growth comparable to minoxidil, showing similar efficacy in promoting hair growth without significant statistical difference.
14 citations
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September 2020 in “Clinical, cosmetic and investigational dermatology” This study found that a hair serum containing amla extract, freeze-dried coconut water, and selenium significantly improved hair growth rate, density, and reduced hair fall among healthy volunteers over 90 days.