Effect of Vitamin D on the Expression of Inflammatory Biomarkers in Cultured Sebocytes Treated with Propionibacterium Acnes or Ultraviolet B Irradiation

January 2016 in “ Annals of Dermatology ”

Weon Ju Lee, Min Ji Kim, Hyo Sub Ryu, Mi Yeung Sohn, Yong Hyun Jang, Seok‐Jong Lee, Do Won Kim

TLDR Vitamin D may help reduce inflammation in acne.

The study investigated the effect of Vitamin D on inflammatory biomarkers in cultured sebocytes exposed to Propionibacterium acnes or Ultraviolet B irradiation. It was found that Vitamin D reduced the expression of inflammatory biomarkers in these conditions, suggesting a potential anti-inflammatory role of Vitamin D in acne treatment. This indicated that Vitamin D might have been beneficial in managing acne by modulating inflammatory responses in sebocytes.

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