Effect of Dihydrotestosterone on the Upregulation of Inflammatory Cytokines in Cultured Sebocytes

    December 2009 in “ Archives of Dermatological Research ”
    Weon Ju Lee, H. Jung, Seong Geun … Jung Chul Kim
    Studysummary In this study, DHT was associated with increased production of proinflammatory cytokines IL-6 and TNF-α in cultured sebocytes, suggesting a role in acne pathophysiology beyond sebum production.
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    Research cited in this study 4

    1. Influence of Substance P on Cultured Sebocytes Archives of Dermatological Research · 2008
    2. Sexual Hormones in Human Skin Hormone and metabolic research · 2007
    3. Acne and Sebaceous Gland Function Clinics in dermatology · 2004
    4. The Human Sebocyte Culture Model Provides New Insights Into Development and Management of Seborrhoea and Acne Dermatology · 1998