Sun-305 Hair Cortisol Measurement: An Innovative Method for Diagnosis and Follow-Up in Patients with Cushing's Disease

April 2020 in “ Journal of the Endocrine Society ”

Natalia Gabriela Deligiannis, Soledad Sosa, Diego González, Carolina Ibar, Darío Jacobsen, Bibiana Fabre, Karina Danilowicz

hair cortisol measurement Cushing’s disease hypercortisolism urinary free cortisol

TLDR Hair cortisol measurement can help diagnose and monitor Cushing’s disease.

The study evaluated hair cortisol measurement (HCM) as an innovative method for diagnosing and monitoring Cushing’s disease (CD), involving 23 CD patients and 50 controls. HCM was proposed as an additional diagnostic test for hypercortisolism, showing acceptable concordance with urinary free cortisol (UFC) levels, despite differences in the evaluation periods. The study found significant differences in HCM values between CD patients and controls, suggesting HCM could be a viable alternative for diagnosing and following up on CD. The study highlighted that HCM could differentiate between controlled and active CD, with higher HCM values associated with active disease.

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Sun-305 Hair Cortisol Measurement: An Innovative Method for Diagnosis and Follow-Up in Patients with Cushing's Disease

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