13 citations
,
November 2024 in “BMC Psychiatry” This study found that women with PCOS have a high prevalence of depression and anxiety, with poor mental well-being linked to both conditions, suggesting the need for mental health screening in these patients.
13 citations
,
August 2019 in “Journal of Ethnopharmacology” This study assessed 11 plants from French Polynesia for their potential development as sustainable natural cosmetics, particularly anti-aging and hair care products, based on their traditional uses and preliminary screening results.
13 citations
,
January 2019 in “Indian Journal of Dermatology” This study found that men with early-onset androgenic alopecia had a higher prevalence of cardiovascular risk factors, indicating that early screening for metabolic syndrome may be beneficial in this population.
12 citations
,
July 2011 in “European Journal of Dermatology” The authors concluded that VSCAPSI, a videodermoscopy-based assessment tool, provides evidence for early diagnosis, differential diagnosis, follow-up, and screening of scalp psoriasis.
11 citations
,
October 2003 in “Postgraduate Medical Journal” This study described four cases of delayed diagnosis of Cushing’s syndrome, highlighting that increased clinical awareness and screening could reduce its associated morbidity and mortality.
8 citations
,
September 2023 in “International Journal of Nanomedicine” In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.
7 citations
,
June 2024 in “iScience” This review highlights the significant role of androgens in the development and progression of cervical cancer, emphasizing the need for further research to understand their impact on the disease and improve prevention and treatment strategies in regions with limited HPV screening.
7 citations
,
May 2023 in “Macromolecular Bioscience” This review discusses recent advancements in using macromolecules for hair loss treatment, highlighting microneedle and nanoparticle delivery systems, tissue-engineered scaffolds for hair follicle regeneration, and artificial skin platforms as drug screening methods.
7 citations
,
December 2014 in “Journal of dermatology” This study found that miR-221 levels in hair shafts were significantly higher in malignant melanoma patients compared to controls, suggesting potential as a non-invasive screening marker.
7 citations
,
September 2013 in “Familial cancer” This review discusses recent insights into Birt–Hogg–Dube syndrome, including the functions of the FLCN gene and clinical recommendations for screening and treatment, but it reports no new experimental results.
6 citations
,
June 2024 in “Skin Appendage Disorders” This study identified associations between alopecia areata and posttraumatic stress disorder, obesity, and alcohol use, reinforcing the need for psychiatric and alcohol use screening in these patients.
6 citations
,
April 2018 in “Transplantation proceedings” This case report describes severe agranulocytosis and alopecia in a Japanese woman after starting azathioprine, highlighting the potential role of NUDT15 genetic screening in preventing adverse reactions to the drug.
6 citations
,
January 2012 in “Breast cancer” This study suggests that breast cancer-associated phospholipids may alter the X-ray diffraction pattern of hair, potentially enabling the development of a sensitive and specific screening test for breast cancer.
5 citations
,
November 2024 in “Cells” This review highlighted that in an in vitro setting, 3D spheroid cultures of fish cells offer a promising alternative to traditional monolayer cultures, potentially advancing research in eco-toxicology, immunology, drug screening, and more by better mimicking in vivo conditions.
5 citations
,
August 2024 in “Drug Discovery Today” This review examines advances in computer-aided drug design for targeting membrane proteins in prostate cancer but reports no new clinical results; it emphasizes the potential of structural insights and compound screening for therapeutic development.
5 citations
,
November 2023 in “Journal of Research in Medical Sciences” This study found that patients with AA who have more severe symptoms may have a higher risk of metabolic syndrome and arterial stiffness, suggesting a need for cardiometabolic disease screening.
5 citations
,
October 2020 in “Bioengineering & translational medicine” This study demonstrates the use of microscopy-guided laser ablation to create a highly structured 3D hydrogel-based organotypic skin model with folliculoid structures, potentially useful for studying hair follicle development or bioactive substance screening.
5 citations
,
March 2019 in “Journal of lipid research” This study reports new fluorogenic ceramidase substrates and highlights RBM14C24:1 as an efficient substrate for neutral ceramidase, while RBM15C18:1 is the best probe for measuring ACER1 and ACER2 activities, potentially aiding high-throughput screening for ceramidase inhibitors.
4 citations
,
December 2022 in “Frontiers in cell and developmental biology” This review discusses the use of zebrafish larvae as an alternative model for studying ototoxicity, facilitating large-scale screening for otoprotective compounds, but reports no new clinical results.
4 citations
,
May 2014 in “European Journal of Dermatology” This study found that severe androgenetic alopecia was associated with metabolic syndrome components in male psoriatic patients, particularly those over 59 years old, suggesting the need for regular screening.
4 citations
,
December 2012 in “Medical Hypotheses” This review discusses the possible link between prediabetes and hair loss, highlighting the need for further studies to evaluate this relationship and suggesting screenings for diabetes in patients with hair loss.
3 citations
,
September 2024 in “Journal of Pre-Clinical and Clinical Research” This study reviews the current understanding of psychiatric disorders in women with PCOS, finding links to the gut-brain axis, neurotransmitter and neuroendocrine dysfunction, and suggests the need for routine mental health screening in these patients.
3 citations
,
January 2024 in “Revista da Associação Médica Brasileira” In this study, the authors reported that depression and anxiety are more prevalent in patients with polycystic ovary syndrome compared to healthy women, reinforcing the need for routine mental health screening in this population.
3 citations
,
March 2023 in “Scientific Reports” This study found that organoid cultures of human epithelial and mesenchymal cells can produce hair peg-like structures, and their growth is enhanced by minoxidil, suggesting potential for hair drug screening.
3 citations
,
October 2021 in “Research Square (Research Square)” This study used in vivo confocal microscopy and a ResNet34 deep learning model to classify meibomian gland images with an AUROC greater than 0.95, indicating its potential for automatic diagnosis and screening of meibomian gland dysfunction.
3 citations
,
July 2021 in “International journal of environmental research and public health/International journal of environmental research and public health” This study reports two cases of Alopecia Universalis as a secondary autoimmune manifestation following Alemtuzumab treatment, highlighting the importance of screening and monitoring for such autoimmune responses.
3 citations
,
April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study presents a new method using primary human lung tissue cells to rapidly identify viral entry factors and therapeutics for SARS-CoV-2, revealing compounds overlooked by conventional screening systems.
3 citations
,
February 2021 in “Experimental dermatology” This study observed that using 3D dermal papilla microtissues enhances hair follicle regeneration and gene expression compared to 2D cultures, indicating their potential for hair growth drug screening.
3 citations
,
April 2019 in “Annals of hepatology” This case report described a peanut allergy transfer from an organ donor to two transplant recipients, emphasizing the need for pre-transplant donor allergy screening.
3 citations
,
April 2015 in “AFRICAN JOURNAL OF BIOTECHNOLOGY” This study found that certain Y-chromosome alleles may influence susceptibility to prostate cancer among Iraqi males, suggesting potential genetic screening markers for the disease.