Osler’s Phenomenon: Misdiagnosing Cushing’s Syndrome

    October 2003 in “ Postgraduate Medical Journal
    P. De, L. M. Evans, M. F. Scanlon, J. S. Davies
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    TLDR Doctors often diagnose Cushing's syndrome late, which worsens symptoms; earlier detection is needed.
    The document from 2003 discusses the issue of misdiagnosing Cushing's syndrome, a condition with symptoms like obesity, diabetes, hirsutism, and adrenal hyperplasia. It presents four case reports where patients had a delayed diagnosis ranging from six months to ten years, leading to worsening symptoms. The delay is attributed to the perceived rarity of the condition, and the authors suggest that increased clinical awareness and appropriate screening could lead to earlier diagnosis. They propose the term "Osler's phenomenon" to describe the misdiagnosis or delay in diagnosing Cushing's syndrome, acknowledging Sir William Osler's early work on the condition.
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