TLDR Androgens increase cervical cancer risk and affect its development.
This review highlights the significant role of androgens in cervical cancer, emphasizing their impact on cellular processes like proliferation and apoptosis, and their interaction with HPV subtypes. Elevated androgen levels are linked to increased cervical cancer risk, particularly in regions with limited HPV screening. The presence of androgen receptors in cervical tissues suggests that androgens are crucial in cervical cancer pathogenesis. The review calls for further research to enhance prevention and treatment strategies, underscoring androgens as a vital factor in cervical cancer etiology and progression.
35 citations
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May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
11 citations
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September 2019 in “Dermatologic Surgery” A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
56 citations
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October 2018 in “Journal of The American Academy of Dermatology” Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
131 citations
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September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
